Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Journal ArticleDOI
Identification of novel dipeptidyl peptidase-IV and angiotensin-I-converting enzyme inhibitory peptides from meat proteins using in silico analysis.
TL;DR: The use of in silico methodologies, peptide databases and software to assess the release of potentially bioactive DPP-IV, renin and ACE-I inhibitory peptides from bovine and porcine meat proteins demonstrating that meat proteins are a suitable resource for the generation of bioactive peptides is demonstrated.
Journal ArticleDOI
Whey protein hydrolysates as a source of bioactive peptides for functional foods – Biotechnological facilitation of industrial scale-up
TL;DR: The requirements of industrial processes regarding peptide release and stability, depending on several process parameters, are summarized, and some enrichment techniques for whey-derived peptides that are potentially applicable to industry are considered.
Journal ArticleDOI
Microbial proteases: Production and application in obtaining protein hydrolysates.
TL;DR: This review aims to describe the production of proteases, the use of microbial proteases in enzymatic hydrolysis, in different industries and to explain the characteristics of such enzymes.
Journal ArticleDOI
Marine Algae-Derived Bioactive Peptides for Human Nutrition and Health
TL;DR: This review presents an overview of marine algae-derived bioactive peptides and especially highlights some key issues, such as in silico proteolysis and quantitative structure-activity relationship studies, in vivo fate of bio active peptides, and novel technologies in bioactive Peptide studies and production.
Book ChapterDOI
Antihypertensive Peptides from Food Proteins
TL;DR: Although hypertension can be controlled by pharmacological agents, it represents a major burden on annual global healthcare costs and it is thought that prevention through lifestyle choices and early treatment for individuals with mild hypertension can significantly reduce global health-care costs.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more