Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Journal ArticleDOI
The Half Maximal Inhibitory Concentration (IC50) Effect of Protein Hydrolysates from Rainbow Trout (Oncorhynchus mykiss) Skin on Enterotoxin A Gene Expression in Staphylococcus aureus
TL;DR: Fish hydrolyzed proteins can provide a new strategy as natural factors in preventing toxin production, due to the high quality and safety of sensitive foods.
Dissertation
Antioxidant and angiotensin converting enzyme inhibitory activities from bovine serum albumin.
TL;DR: Novel findings are reported showing that BSA peptides have antioxidant and ACE inhibitory activities that could potentially be used as food supplements and pharmaceutical agents.
Journal ArticleDOI
Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets
TL;DR: A series of urea/thiourea derivatives synthesized by using peptides conjugated to 3-(1-piperazinyl)-1,2-benzisothiazole and their structure was characterized by analytical and spectral methods.
Journal ArticleDOI
Desalination of Antioxidant Peptides from Pinctada fucata Using C18 Chromatographic Column
TL;DR: In this paper, the desalination rate and the antioxidant activity were used to analyze the effect of desaline conditions. And the results showed that the optimum conditions for desalting are loading 2ml of sample with concentration of 100 mg/ml, flow rate of 2 ml/min, 0.1% TFA as mobile phase with pH 6.5 in 0-4.5min and 80% methanol in 4.5-30min.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
Related Papers (5)
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more