Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Digestión gastrointestinal de proteínas alimentarias y mecanismos de acción de péptidos con efecto sobre la salud digestiva / gastrointestinal digestion of food proteins and mechanisms of action of peptides on digestive health
TL;DR: In this paper, the effects of bioactive peptides on the digestive tract have been studied by a double approach, where the authors investigated not only the modifications that food proteins and peptides undergo during the gastrointestinal digestion, but also the mechanisms of action involved in the biological function that peptides might exert due to their contact with digestive cells and receptors.
Journal ArticleDOI
Structural, spectroscopic, in silico, in vitro and DNA binding evaluations of tyrosyl-lysyl-threonine.
Bilge Bicak,Serda Kecel Gündüz,Yasemin Budama Kilinc,Petra Imhof,Bahar Gok,Gizem Akman,Aysen E. Ozel +6 more
TL;DR: In this paper, the molecular structure and DNA binding interaction of the tyrosyl-lysylthreonine (YKT) tripeptide, which has anticancer, antioxidant and analgesic properties, using various in silico (MD, QM, molecular docking), spectroscopic (UV, FT-IR, FTIR-ATR, Raman, gel electrophoresis) and in vitro (MCF-7 and HeLa cancer cell lines and BEAS-2B cell line) methods.
Journal ArticleDOI
Preliminary investigations in vitro ace-inhibitory activities of tryptic peptides produced from cold press deoiled hazelnut meals
İbrahim Gülseren,Bilal Çakır +1 more
TL;DR: Corylus avellana L. as discussed by the authors proteince zengin bir kaynaktir ve soguk pres yonteminde ortaya cikan findik posalarindan, findik proteini konsantreleri uretilmis ve bu konsistentreler triptik hidrolize (37°C) tabi tutulmustur.
Book ChapterDOI
Determining Functional Properties and Sources of Recently Identified Bioactive Food Components: Oligosaccharides, Glycolipids, Glycoproteins, and Peptides
Journal ArticleDOI
Kinetic analysis of cellular internalization and expulsion of unstructured D-chirality cell penetrating peptides
Manibarathi Vaithiyanathan,Hannah C. Hymel,Nora Safa,Olivia M. Sanchez,Jacob H. Pettigrew,Cole S. Kirkpatrick,Ted J. Gauthier,Adam T. Melvin +7 more
TL;DR: In this paper, a series of time, concentration, temperature, and energy dependent studies was conducted to investigate CPP internalization using a seriesof time and concentration dependent studies, resulting in a three-fold increase in uptake and 50-fold increased in stability of D-chirality peptides over L-Chirality counterparts.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more