Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Journal ArticleDOI
Antifungal Peptides as Therapeutic Agents.
Miguel Fernández de Ullivarri,Miguel Fernández de Ullivarri,Sara Arbulu,Sara Arbulu,Enriqueta Garcia-Gutierrez,Enriqueta Garcia-Gutierrez,Paul D. Cotter,Paul D. Cotter +7 more
TL;DR: This review provides an overview of the bioactivity and classification of AFPs (natural and synthetic), as well as their mode of action and advantages over current antifungal drugs, and evaluates the current and potential applications of these peptides.
Journal ArticleDOI
Innovative applications of high-intensity ultrasound in the development of functional food ingredients: Production of protein hydrolysates and bioactive peptides
TL;DR: In this article, the authors reviewed recent advances in food science and technology on the application of high-intensity ultrasound (HIU) for the enhancement of enzymatic hydrolysis of proteins of both animal and plant origin.
Journal ArticleDOI
Improvement of the stability and activity of immobilized trypsin on modified Fe3O4 magnetic nanoparticles for hydrolysis of bovine serum albumin and its application in the bovine milk.
TL;DR: Immobilized trypsin (TR) was more stable than the free one and demonstrated higher enzymatic activity at elevated temperatures (45-55°C) and in the alkaline pH region (6-10.5) while Fe3O4 NPs-GA-TR retained about 64% of its initial activity during the same storage period.
Journal ArticleDOI
Use of Proteomics and Peptidomics Methods in Food Bioactive Peptide Science and Engineering
Janet Carrasco-Castilla,Alan Javier Hernández-Álvarez,Cristian Jiménez-Martínez,Gustavo F. Gutiérrez-López,Gloria Dávila-Ortiz +4 more
TL;DR: Recent analytical tools used for studying various aspects of food-derived biopeptides, emphasizing their production at laboratory and industrial scale are described.
Journal ArticleDOI
Bioinformatics and peptidomics approaches to the discovery and analysis of food-derived bioactive peptides
TL;DR: Together, bioinformatics and peptidomics approaches provide a low-cost and effective means of predicting, profiling, and screening bioactive protein hydrolysates and peptides from food.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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Food-derived peptides with biological activity: from research to food applications.
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