Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Journal ArticleDOI
The Identification of a Novel Peptide Derived from Lactoferrin Isolated from Camel Milk with Potential Antimicrobial Activity
TL;DR: The results showed that the newly-identified peptide had no toxicity against the cell line, and it seems that the growth of S. aureus, P. aeruginosa, and A. baumannii was not affected by Pepsin-Camel-Lac1 treatment in the bacterial culture medium.
Dissertation
Development of bioactive bread enriched with a seaweed peptide fraction with potential heart-health effects
TL;DR: The extraction and isolation of renin and PAF-AH inhibitory peptides from the macroalgae Palmaria palmata was carried out and the effectiveness of the isolated renin inhibitory tridecapeptide IRLIIVLMPILMA was explored.
Review Article Bioactive Peptides: A Review
TL;DR: The properties of bioactive peptides especially derived from milk, classified as antimicrobial, antithrombotic, antihypertensive, opioid, immunomodulatory, mineral binding and antioxidative, are described.
Journal ArticleDOI
A Peptides Prediction Methodology for Tertiary Structure Based on Simulated Annealing
Juan Paulo Sánchez-Hernández,Juan Frausto-Solís,Juan Javier González-Barbosa,Diego A. Soto-Monterrubio,Fanny G. Maldonado-Nava,Guadalupe Castilla-Valdez +5 more
TL;DR: GRSA-SSP methodology is presented, that implements a secondary structure prediction to build an initial model and refine it with HSA algorithms and is compared with PEP-FOLD3, I-TASSER, QUARK, and Rosetta, showing that it competes in small peptides except when predicting the largest peptides.
Journal ArticleDOI
Production of peptides as generic drugs: a patent landscape of octreotide.
Giuseppina Sabatino,Ivan Guryanov,Andrea Rombecchi,Jacopo Zanon,Antonio Ricci,Walter Cabri,Anna Maria Papini,Paolo Rovero +7 more
TL;DR: Analysis of various patents filed to date allows us to see the trend in simplification of the synthetic approaches from the labor intensive syntheses in solution to the more versatile and rapid solid-phase methods.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more