Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
More filters
Journal ArticleDOI
Savinase, the most suitable enzyme for releasing peptides from lentil (Lens culinaris var. Castellana) protein concentrates with multifunctional properties.
TL;DR: The ACE-inhibitory and antioxidant activities of S2 were significantly improved after in vitro gastrointestinal digestion, which could encourage value-added utilization of lentil proteins for the formulation of functional foods and nutraceuticals.
Journal ArticleDOI
Pharmaceutical applications of bioactive peptides
Michael K. Danquah,Dominic Agyei +1 more
TL;DR: This critical review discusses some potential therapeutic applications of bioactive peptides in the light of advances in general biopharmaceutical production based on proteomics and genomics.
Journal ArticleDOI
Exploration of collagen recovered from animal by-products as a precursor of bioactive peptides: Successes and challenges.
TL;DR: The opportunity to utilize collagen peptides as high value-added bio-functional ingredients in the food industry is discussed, including antihypertensive, antioxidant and antidiabetic activities, and beneficial effects on bone, joint and skin health.
Journal ArticleDOI
Learnings from quantitative structure–activity relationship (QSAR) studies with respect to food protein-derived bioactive peptides: a review
TL;DR: It appears to date that only a limited number of QSAR studies conducted with BAPs have subsequently carried out confirmatory studies and evaluated promising peptide sequences in vivo, suggesting that more research is needed in order to advance knowledge in the area of BAP discovery usingQSAR.
Journal ArticleDOI
Production of Bioactive Peptides from Lactic Acid Bacteria: A Sustainable Approach for Healthier Foods
María Georgina Venegas-Ortega,Adriana C. Flores-Gallegos,José L. Martínez-Hernández,Cristóbal N. Aguilar,Guadalupe Virginia Nevárez-Moorillón +4 more
TL;DR: The multifunctional proteinaceous compounds generated by LAB metabolism are described and a strategy to use a single-step production process, using an alternative protein-based media is discussed, which will provide economic advantages in fermentation processes and will also provide an environmental alternative to industrial waste valorization.
References
More filters
Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
Related Papers (5)
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more