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Journal ArticleDOI

Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.

Dominic Agyei, +1 more
- 01 May 2011 - 
- Vol. 29, Iss: 3, pp 272-277
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.
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This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.

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Citations
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Propiedades biológicas de péptidos derivados del colágeno de organismos marinos

TL;DR: The authors recopila hallazgos mas recientes sobre los efectos beneficos of peptidos derivados of colageno and gelatina of especies marinas, con enfasis en las caracteristicas estructurales that definen sus propiedades antioxidantes, antihipertensivas, anticancerigenas, antimicrobianas, neuroprotectoras, etc.
Journal ArticleDOI

Cryptic Host Defense Peptides: Multifaceted Activity and Prospects for Medicinal Chemistry

TL;DR: This review focuses on cryptic HDPs, molecules derived specifically from proteolytic processing of endogenous precursor proteins, and explores the biological activity of such molecules and further discusses the development of optimized sequences based on these natural crypticHDPs.
Journal ArticleDOI

Bioactive peptides derived from fermented foods: Preparation and biological activities

TL;DR: In this paper , a review of bioactive peptides in fermented foods is presented, followed by a discussion of the shortcomings in current research and future directions to provide a foundation for applications of BAPs in fermentation foods in the food and pharmaceutical fields.
Journal ArticleDOI

Enzymatic production and analysis of antioxidative protein hydrolysates

TL;DR: This review provides an overview on the production and analysis techniques of antioxidative peptides from food proteins and pros and cons of various strategies for peptide separation and antioxidative measurement.
Journal ArticleDOI

Peptidases from Maclura Pomifera for Preparation of Food Protein Hydrolysates: Purification by Single-Step Chromatography and Characterization of Pomiferin I

TL;DR: The objective was to isolate peptidases from the latex of Maclura pomifera fruits and use them to hydrolyze food proteins, as well as to purify and characterize the main peptidase, which showed only partial homology of p Pomiferin I with a serine peptid enzyme from a species of the same family.
References
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Journal ArticleDOI

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.

TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI

Bioactive peptides: Production and functionality

TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
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Food-derived peptides with biological activity: from research to food applications.

TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI

Development and biological activities of marine-derived bioactive peptides: A review

TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI

Bioactive peptides and proteins from foods: indication for health effects.

TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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