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Open AccessJournal ArticleDOI

Interobserver agreement for the assessment of handicap in stroke patients.

J. C. van Swieten, +4 more
- 01 May 1988 - 
- Vol. 19, Iss: 5, pp 604-607
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TLDR
The results confirm the value of the modified Rankin scale in the assessment of handicap in stroke patients; nevertheless, further improvements are possible.
Abstract
Interobserver agreement for the assessment of handicap in stroke patients was investigated in a group of 10 senior neurologists and 24 residents from two centers. One hundred patients were separately interviewed by two physicians in different combinations. The degree of handicap was recorded by each observer on the modified Rankin scale, which has six grades (0-5). The agreement rates were corrected for chance (kappa statistics). Both physicians agreed on the degree of handicap in 65 patients; they differed by one grade in 32 patients and by two grades in 3 patients. Kappa for all pairwise observations was 0.56; the value for weighted kappa (with quadratic disagreement weights) was 0.91. Our results confirm the value of the modified Rankin scale in the assessment of handicap in stroke patients; nevertheless, further improvements are possible.

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Thrombolysis with Alteplase 3 to 4.5 Hours After Acute Ischemic Stroke

TL;DR: As compared with placebo, intravenous alteplase administered between 3 and 4.5 hours after the onset of symptoms significantly improved clinical outcomes in patients with acute ischemic stroke; altePlase was more frequently associated with symptomatic intracranial hemorrhage.
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A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

TL;DR: In patients with acute ischemic stroke caused by a proximal intracranial occlusion of the anterior circulation, intraarterial treatment administered within 6 hours after stroke onset was effective and safe.
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International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms : a randomised trial

Andrew J. Molyneux
- 26 Oct 2002 - 
TL;DR: In patients with a ruptured intracranial aneurysm, for which endov vascular coiling and neurosurgical clipping are therapeutic options, the outcome in terms of survival free of disability at 1 year is significantly better with endovascular coiling.
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Classification and natural history of clinically identifiable subtypes of cerebral infarction

TL;DR: There were striking differences in natural history between the groups and the findings have important implications for the planning of stroke treatment trials and suggest that various therapies could be directed specifically at the subgroups.
References
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Journal ArticleDOI

The measurement of observer agreement for categorical data

TL;DR: A general statistical methodology for the analysis of multivariate categorical data arising from observer reliability studies is presented and tests for interobserver bias are presented in terms of first-order marginal homogeneity and measures of interob server agreement are developed as generalized kappa-type statistics.
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A Coefficient of agreement for nominal Scales

TL;DR: In this article, the authors present a procedure for having two or more judges independently categorize a sample of units and determine the degree, significance, and significance of the units. But they do not discuss the extent to which these judgments are reproducible, i.e., reliable.
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Weighted kappa: Nominal scale agreement provision for scaled disagreement or partial credit.

TL;DR: The Kw provides for the incorpation of ratio-scaled degrees of disagreement (or agreement) to each of the cells of the k * k table of joi.
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ASSESSMENT OF OUTCOME AFTER SEVERE BRAIN DAMAGE: A Practical Scale

TL;DR: In this article, a five-point scale is described, which includes death, persistent vegetative state, severe disability, moderate disability, and good recovery, and duration as well as intensity of disability should be included in an index of ill-health.
Journal ArticleDOI

Cerebral vascular accidents in patients over the age of 60. II. Prognosis.

TL;DR: A survey was carried out on a number of 'untreated' cases seen shortly after the onset of a cerebral vascular accident, with particular reference to the presence of signs which had prognostic value, to enable the investigator to assess the results of specific forms of treatment.
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