Journal ArticleDOI
KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for Glomerulonephritis
Laurence H. Beck,Andrew S. Bomback,Michael J. Choi,Lawrence B. Holzman,Carol A. Langford,Laura H. Mariani,Michael J. Somers,Howard Trachtman,Meryl Waldman +8 more
TLDR
This commentary, developed by a panel of clinical experts convened by the National Kidney Foundation, attempts to put the KDIGO guideline for glomerulonephritis into the context of the US health care system and supports the vast majority of the recommendations.About:
This article is published in American Journal of Kidney Diseases.The article was published on 2013-09-01. It has received 441 citations till now. The article focuses on the topics: Guideline & Health care.read more
Citations
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Journal ArticleDOI
Primary Membranous Nephropathy
TL;DR: Clinically, 80% of patients with PMN present with nephrotic syndrome and 20% with non-nephrotic proteinuria, and substantial clinical and experimental data now suggests these antibodies are pathogenic.
Journal ArticleDOI
Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicentre, double-blind, randomised, placebo-controlled trial.
Kazumoto Iijima,Mayumi Sako,Kandai Nozu,Rintaro Mori,Nao Tuchida,Koichi Kamei,Kenichiro Miura,Kunihiko Aya,Koichi Nakanishi,Yoshiyuki Ohtomo,Shori Takahashi,Ryojiro Tanaka,Hiroshi Kaito,Hidefumi Nakamura,Kenji Ishikura,Shuichi Ito,Yasuo Ohashi +16 more
TL;DR: Rituximab is an effective and safe treatment for childhood-onset, complicated FRNS and SDNS and the relapse-free period was the primary endpoint and safety endpoints were frequency and severity of adverse events.
Journal ArticleDOI
A Proposal for a Serology-Based Approach to Membranous Nephropathy
TL;DR: It is proposed that an individualized serology-based approach to MN, used to complement and refine the traditional proteinuria-driven approach, will improve the outcome in this disease.
Journal ArticleDOI
Trimethoprim-sulfamethoxazole (co-trimoxazole) for the prevention of relapses of Wegener's granulomatosis
TL;DR: Treatment with co-trimoxazole reduces the incidence of relapses in patients with Wegener's granulomatosis in remission and is identified as an independent factor associated with prolonged disease-free survival and a positive antineutrophil cytoplasmic antibody test at the start of treatment as a risk factor for relapse.
Journal ArticleDOI
Chronic kidney disease in children
TL;DR: Factors related to CKD that start during childhood and require appropriate treatments in order to optimize health outcomes and transition to nephrologist management in adult life are discussed.
References
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The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents
Bonita Falkner,Stephen R. Daniels,Joseph T. Flynn,Samuel S. Gidding,Lee A. Green,Julie R. Ingelfinger,Ronald M. Lauer,Bruce Z. Morgenstern,Ronald J. Portman,Ronald J. Prineas,Albert P. Rocchini,Bernard Rosner,Alan R. Sinaiko,Nicolas Stettler,Elaine M. Urbina,Edward J. Roccella,Tracey R. Hoke,Carl E. Hunt,Gail D. Pearson,Joanne Karimbakas,Ann Horton +20 more
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Wegener granulomatosis : an analysis of 158 patients
Gary S. Hoffman,Gail S. Kerr,Randi Y. Leavitt,Claire W. Hallahan,Robert S. Lebovics,William D. Travis,Menachem Rottem,Anthony S. Fauci +7 more
TL;DR: The course of Wegener granulomatosis has been dramatically improved by daily treatment with cyclophosphamide and glucocorticoids, and has led to increasing concerns about toxicity resulting from prolonged cycloph phosphamide therapy and has encouraged investigation of other therapeutic regimens.
Journal ArticleDOI
Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis
John H. Stone,Peter A. Merkel,Robert Spiera,Philip Seo,Carol A. Langford,Gary S. Hoffman,Cees G. M. Kallenberg,E. William St. Clair,Anthony M. Turkiewicz,Nadia K. Tchao,Lisa Webber,Linna Ding,Lourdes P. Sejismundo,Kathleen Mieras,David Weitzenkamp,David Ikle,Vicki Seyfert-Margolis,Mark Mueller,Paul Brunetta,Nancy B. Allen,Fernando C. Fervenza,Duvuru Geetha,Karina A. Keogh,Eugene Y. Kissin,Paul A. Monach,Tobias Peikert,Coen A. Stegeman,Steven R. Ytterberg,Ulrich Specks +28 more
TL;DR: Rituximab therapy was not inferior to daily cyclophosphamide treatment for induction of remission in severe ANCA-associated vasculitis and may be superior in relapsing disease.
Journal ArticleDOI
Wegener's granulomatosis: Prospective clinical and therapeutic experience with 85 patients for 21 years
TL;DR: It is shown that long-term remissions can be induced and maintained in an extremely high number of patients by the combination of daily cyclophosphamide and alternate-day prednisone therapy.
Journal ArticleDOI
Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B
George K. K. Lau,Teerha Piratvisuth,Kang Xian Luo,Patrick Marcellin,Satawat Thongsawat,Graham Cooksley,Edward Gane,Michael W. Fried,Wan Cheng Chow,Seung Woon Paik,Wen Yu Chang,Thomas Berg,Robert Flisiak,Philip McCloud,Nigel Pluck +14 more
TL;DR: In patients with H beAg-positive chronic hepatitis B, peginterferon alfa-2a offers superior efficacy over lamivudine, on the basis of HBeAg seroconversion, HBV DNA suppression, and HBsAg serconversion.
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Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis
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