Lactococcal bacteriocins - mode of action and immunity
TLDR
The lactococcal bacteriocins are hydrophobic cationic peptides, which form pores in the cytoplasmic membrane of sensitive cells.About:
This article is published in Trends in Microbiology.The article was published on 1995-08-01 and is currently open access. It has received 78 citations till now. The article focuses on the topics: Bacteriocin & Antimicrobial peptides.read more
Citations
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Journal ArticleDOI
Molecular identification of bacteriocins produced by Lactococcus lactis dairy strains and their technological and genotypic characterization
Maria Barbara Pisano,Maria Elisabetta Fadda,Roberta Melis,Maria Laura Ciusa,S. Viale,Maura Deplano,Sofia Cosentino +6 more
TL;DR: The autochthonous bacteriocinogenic isolates from Sardinian dairy products described in this work may potentially find application as starter, co-starter or protective adjunct cultures in the manufacturing of cheeses.
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Características da bacteriocina produzida por Lactococcus lactis ssp. hordniae CTC 484 e seu efeito sobre Listeria monocytogenes em carne bovina
TL;DR: The bacteriocin inhibited closely related lactic acid bacterium (Lactobacillus helveticus), but also pathogenic microorganisms (Staphylococcus aureus, Listeria monocytogenes, Bacillus cereus, Clostridium perfringens, and Enterococcus faecalis) as mentioned in this paper.
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Spontaneous bacteriocin resistance in Listeria monocytogenes as a susceptibility screen for identifying different mechanisms of resistance and modes of action by bacteriocins of lactic acid bacteria.
Sunita Macwana,Peter M. Muriana +1 more
TL;DR: A methodical approach is identified to classify bacteriocins into functional groups based on mechanism of resistance (i.e., mode of action) that could be used for identifying the best mixture of bacteriOCins for use as biopreservatives.
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Transcriptional analysis of bacteriocin production by malt isolate Lactobacillus sakei 5
Anne Vaughan,Jim O' Mahony,Vincent G. H. Eijsink,Mary O' Connell-Motherway,Douwe van Sinderen +4 more
TL;DR: Primer extension transcriptional analysis pointed to the existence of three distinct promoters within the sakacin TX locus, indicating that the three-component regulatory system in this locus is atypical in the sense that it is divided into a pheromone-specifying operon and an operon containing the genes for the histidine protein kinase and response regulator.
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Effets combinés de la nisine, de l'acide lactique et du sorbate de potassium sur les spores de Bacillus licheniformis dans le lait
TL;DR: In this paper, the inhibitory activities of nisin and/or potassium sorbate on Bacillus licheniformis spores were studied in milk acidified with lactic acid, at 37 oc.
References
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Journal ArticleDOI
Genetics of bacteriocins produced by lactic acid bacteria
TL;DR: The biochemical and genetic characteristics of these antimicrobial proteins are reviewed and common elements are discussed between the different classes of bacteriocins produced by these Gram-positive bacteria.
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Bacteriocins of lactic acid bacteria
TL;DR: The range of inhibitory activity by bacteriocins of lactic acid bacteria can be either narrow, inhibiting only those strains that are closely related to the producer organism, or wide, inhibited a diverse group of Gram-positive microorganisms as mentioned in this paper.
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Nisin treatment for inactivation of Salmonella species and other gram-negative bacteria.
TL;DR: It is demonstrated that nisin is bactericidal to Salmonella species and that the observed inactivation can be demonstrated in other gram-negative bacteria.
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Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity
TL;DR: Transcription analyses of several L. lactis strains indicated that an expression product of the nisA gene, together with NisR, is required for the activation of nisinA transcription, indicating that NisI plays a role in the immunity mechanism.
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Mode of action of the peptide antibiotic nisin and influence on the membrane potential of whole cells and on cytoplasmic and artificial membrane vesicles
E Ruhr,Hans-Georg Sahl +1 more
TL;DR: The data suggest that the cytoplasmic membrane is the primary target and that membrane disruption accounts for the bactericidal action of nisin.