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Open AccessJournal ArticleDOI

Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain

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TLDR
The analgesia obtained from a low dose of delta-9-tetrahydrocannabinol (1.29%) in patients, most of whom were experiencing neuropathic pain despite conventional treatments, is a clinically significant outcome and the effect sizes on cognitive testing were consistent with this minimal dose.
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This article is published in The Journal of Pain.The article was published on 2013-02-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Analgesic & Neuropathic pain.

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Patent

Methods, devices and systems for pulmonary delivery of active agents

TL;DR: In this paper, a system that includes a metered dose inhaler device for pulmonary delivering to a subject at least one pre-determined vaporized amount of at least 1 pharmacologically active agent being in a plant material, wherein vaporization is effected by controllably heating the plant material so as to vaporize a pre-defined amount of the agent, was presented.
Journal ArticleDOI

The effects of cannabis, cannabinoids, and their administration routes on pain control efficacy and safety: A systematic review and network meta-analysis

TL;DR: The use of cannabis and cannabinoids via certain administration routes could reduce different types of pain and product developers could consider the findings as part of their product design so that the effective route of Cannabis and cannabinoids for pain control can be achieved.
Journal ArticleDOI

Prevalence and correlates of “Vaping” as a route of cannabis administration in medical cannabis patients

TL;DR: Vaping appears to be relatively common among medical cannabis patients, but is seldom used as the sole route of cannabis administration, and the importance of monitoring trends in vaping and other substance use behaviors in this population is highlighted.
Patent

Drug dose cartridge for an inhaler device

TL;DR: In this paper, the authors described a system for preparing, managing, and/or administering metered doses of substances for vaporized administration, including a heating element integrated into the cartridge in close contact with the botanical substance.
Journal ArticleDOI

Effect of Vaporized Cannabis on Exertional Breathlessness and Exercise Endurance in Advanced Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial.

TL;DR: Single‐dose inhalation of vaporized cannabis had no clinically meaningful positive or negative effect on airway function, exertional breathlessness, and exercise endurance in adults with advanced COPD.
References
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Journal ArticleDOI

The PHQ-9: validity of a brief depression severity measure.

TL;DR: In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 is also a reliable and valid measure of depression severity, which makes it a useful clinical and research tool.
Book

Harrison's Principles of Internal Medicine

TL;DR: In this article, Cardinal Manifestations of Disease Genetics and Disease Clinical Pharmacology Nutrition Infectious Disease Disorders Of The Cardiovascular System Disorders Of the Kidney And Urinary Tract Disorders Of Gastrointestinal System Disorders of The Immune System, Connective Tissue And Joints Hematology And Oncology Endocrinology And Metabolism Neurologic Disorders Environmental And Occupational Hazards.
Journal ArticleDOI

Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale

TL;DR: Using a standard outcome across chronic pain studies would greatly enhance the comparability, validity, and clinical applicability of these studies, and the application of these results to future studies may provide a standard definition of clinically important improvement in clinical trials of chronic pain therapies.
Journal ArticleDOI

Handbook of neuropsychology

Anna Berti
- 01 Jul 1992 - 
Journal ArticleDOI

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

TL;DR: Treatment needs to move from merely suppressing symptoms to a disease-modifying strategy aimed at both preventing maladaptive plasticity and reducing intrinsic risk.
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