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Open AccessJournal ArticleDOI

Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain

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TLDR
The analgesia obtained from a low dose of delta-9-tetrahydrocannabinol (1.29%) in patients, most of whom were experiencing neuropathic pain despite conventional treatments, is a clinically significant outcome and the effect sizes on cognitive testing were consistent with this minimal dose.
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This article is published in The Journal of Pain.The article was published on 2013-02-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Analgesic & Neuropathic pain.

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Citations
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The Effects of Cannabis Among Adults With Chronic Pain and an Overview of General Harms: A Systematic Review

TL;DR: The objectives of this systematic review were to assess the efficacy of cannabis for treating chronic pain and to provide a broad overview of the short- and long-term physical and mental health effects of cannabis use in Chronic pain and general patient populations.
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The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain

TL;DR: Preclinical and clinical evidence of various endocannabinoid system targets as potential therapeutic strategies for inflammatory and neuropathic pain conditions are examined.
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Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

TL;DR: A systematic review and meta-analysis of all randomized controlled trials of Cannabis-based medicines suggests that CBMs might be effective for chronic pain treatment, based on limited evidence, primarily for neuropathic pain patients.
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Cannabinoids and Pain: New Insights From Old Molecules

TL;DR: The evidence from current research supports the use of medical cannabis in the treatment of chronic pain in adults and calls for larger well-designed studies to determine the long-term efficacy and long- term safety of cannabis/cannabinoids.
References
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Journal ArticleDOI

The PHQ-9: validity of a brief depression severity measure.

TL;DR: In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 is also a reliable and valid measure of depression severity, which makes it a useful clinical and research tool.
Book

Harrison's Principles of Internal Medicine

TL;DR: In this article, Cardinal Manifestations of Disease Genetics and Disease Clinical Pharmacology Nutrition Infectious Disease Disorders Of The Cardiovascular System Disorders Of the Kidney And Urinary Tract Disorders Of Gastrointestinal System Disorders of The Immune System, Connective Tissue And Joints Hematology And Oncology Endocrinology And Metabolism Neurologic Disorders Environmental And Occupational Hazards.
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Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale

TL;DR: Using a standard outcome across chronic pain studies would greatly enhance the comparability, validity, and clinical applicability of these studies, and the application of these results to future studies may provide a standard definition of clinically important improvement in clinical trials of chronic pain therapies.
Journal ArticleDOI

Handbook of neuropsychology

Anna Berti
- 01 Jul 1992 - 
Journal ArticleDOI

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

TL;DR: Treatment needs to move from merely suppressing symptoms to a disease-modifying strategy aimed at both preventing maladaptive plasticity and reducing intrinsic risk.
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