Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain
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TLDR
The analgesia obtained from a low dose of delta-9-tetrahydrocannabinol (1.29%) in patients, most of whom were experiencing neuropathic pain despite conventional treatments, is a clinically significant outcome and the effect sizes on cognitive testing were consistent with this minimal dose.About:
This article is published in The Journal of Pain.The article was published on 2013-02-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Analgesic & Neuropathic pain.read more
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Cannabis for pain in orthopedics: a systematic review focusing on study methodology
Kim Madden,Annie George,Niek J. van der Hoek,Felipe Moreira Borim,George Mammen,Mohit Bhandari +5 more
TL;DR: Variability in the methodologies used in cannabis research makes it challenging to draw conclusions about dosing, routes and frequency of administration, but most of the existing evidence suggests that medical cannabis use is effective, but this efficacy has been demonstrated only when either there is no comparator or cannabis is compared with placebo.
Journal ArticleDOI
Cannabis and the skin.
TL;DR: The current research, possible cutaneous adverse effects, and future directions for cannabinoids and their use in skin cancer, acne, psoriasis, pruritus, dermatitis, scleroderma, dermatomyositis, cutaneous lupus erythematous, epidermolysis bullosa, pain, and wound healing are reviewed.
Journal ArticleDOI
The role of cannabinoids in pain control: the good, the bad, and the ugly.
TL;DR: Results from studies testing botanical and synthetic cannabinoids in different pain syndromes are mixed; cannabinoids appear to be most effective in controlling neuropathic pain, allodynia, medication-rebound headache, and chronic noncancer pain, but do not seem to offer any advantage over nonopioid analgesics for acute pain.
Journal ArticleDOI
Cannabis based medicines and cannabis dependence: A critical review of issues and evidence.
Anne Katrin Schlag,Chandni Hindocha,Chandni Hindocha,Rayyan Zafar,David J. Nutt,H. Valerie Curran,H. Valerie Curran +6 more
TL;DR: In this article, the authors provide a review of the current research to determine if, how and to what extent, concerns about problems of dependence in recreational cannabis users apply to prescribed medical users.
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The Association Between Cannabis Use and Aberrant Behaviors During Chronic Opioid Therapy for Chronic Pain.
David J DiBenedetto,Valerie F Weed,Kelly M Wawrzyniak,Matthew Finkelman,Jenelle Paolini,Michael E. Schatman,David Herrera,Ronald J. Kulich +7 more
TL;DR: Conurrent use of cannabis and opioids by patients with chronic pain appears to indicate higher risk for opioid misuse, and closer monitoring for opioid-related aberrancy is indicated for this group of patients.
References
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Journal ArticleDOI
The PHQ-9: validity of a brief depression severity measure.
TL;DR: In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 is also a reliable and valid measure of depression severity, which makes it a useful clinical and research tool.
Book
Harrison's Principles of Internal Medicine
TL;DR: In this article, Cardinal Manifestations of Disease Genetics and Disease Clinical Pharmacology Nutrition Infectious Disease Disorders Of The Cardiovascular System Disorders Of the Kidney And Urinary Tract Disorders Of Gastrointestinal System Disorders of The Immune System, Connective Tissue And Joints Hematology And Oncology Endocrinology And Metabolism Neurologic Disorders Environmental And Occupational Hazards.
Journal ArticleDOI
Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
TL;DR: Using a standard outcome across chronic pain studies would greatly enhance the comparability, validity, and clinical applicability of these studies, and the application of these results to future studies may provide a standard definition of clinically important improvement in clinical trials of chronic pain therapies.
Journal ArticleDOI
Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage
TL;DR: Treatment needs to move from merely suppressing symptoms to a disease-modifying strategy aimed at both preventing maladaptive plasticity and reducing intrinsic risk.