Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain
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TLDR
The analgesia obtained from a low dose of delta-9-tetrahydrocannabinol (1.29%) in patients, most of whom were experiencing neuropathic pain despite conventional treatments, is a clinically significant outcome and the effect sizes on cognitive testing were consistent with this minimal dose.About:
This article is published in The Journal of Pain.The article was published on 2013-02-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Analgesic & Neuropathic pain.read more
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The grass is not always greener: a multi-institutional pilot study of marijuana use and acute pain management following traumatic injury
Kristin Salottolo,Laura Peck,Allen Tanner,Matthew M. Carrick,Robert Madayag,Emmett McGuire,David Bar-Or +6 more
TL;DR: Preliminary data suggest that marijuana use, especially chronic use, may affect pain response to injury by requiring greater use of opioid analgesia.
Journal ArticleDOI
An Ethical Exploration of Barriers to Research on Controlled Drugs
Michael H. Andreae,Evelyn Rhodes,Tyler Bourgoise,George M. Carter,Rob White,Debbie Indyk,Henry S. Sacks,Rosamond Rhodes +7 more
TL;DR: The ethical, social, and regulatory barriers that may hinder research on therapeutic potential of certain controversial controlled substances like marijuana, heroin, or ketamine are examined and an empirical research agenda is proposed to provide an evidentiary basis for ethical reasoning.
Journal ArticleDOI
The pharmacokinetics, efficacy, and safety of a novel selective-dose cannabis inhaler in patients with chronic pain: A randomized, double-blinded, placebo-controlled trial.
Shlomo Almog,Judith Aharon-Peretz,Judith Aharon-Peretz,Simon Vulfsons,Miri Ogintz,Hadas Abalia,Tal Lupo,Yael Hayon,Elon Eisenberg +8 more
TL;DR: Evidence suggests that cannabis‐based medicines are an effective treatment for chronic pain in adults, and a metered‐dose cannabis inhaler delivered precise and low THC doses produced a dose‐dependent and safe analgesic effect in patients with neuropathic pain/ complex‐regional pain syndrome.
Journal ArticleDOI
An Overview of Pharmacologic Management of Chronic Pain
Benjamin R. Beal,Mark S. Wallace +1 more
TL;DR: Intrathecal drug delivery systems can deliver some of these medications directly to their primary site of action while minimizing the side effects seen with systemic administration.
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Therapeutic potential of medicinal marijuana: an educational primer for health care professionals.
Yara Mouhamed,Andrey Vishnyakov,Bessi Qorri,Manpreet Sambi,SM Signy Frank,Catherine Nowierski,Anmol Lamba,Umrao Bhatti,Myron R. Szewczuk +8 more
TL;DR: The purpose of this paper is to offer physicians an educational tool that provides a necessary, evidence-based analysis of the therapeutic potential of MM and to ensure physicians are making decisions on the therapeutic use of MM in good faith.
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