Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain
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TLDR
The analgesia obtained from a low dose of delta-9-tetrahydrocannabinol (1.29%) in patients, most of whom were experiencing neuropathic pain despite conventional treatments, is a clinically significant outcome and the effect sizes on cognitive testing were consistent with this minimal dose.About:
This article is published in The Journal of Pain.The article was published on 2013-02-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Analgesic & Neuropathic pain.read more
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Development and validation of an open-source, disposable, 3D-printed in vitro environmental exposure system for Transwell culture inserts.
Abiram Chandiramohan,Mohammadhossein Dabaghi,Jennifer A. Aguiar,Nicholas Tiessen,Mary Stewart,Quynh T. Cao,Jenny P. Nguyen,Nima Makhdami,Gerard Cox,Andrew C. Doxey,Andrew C. Doxey,Jeremy A. Hirota +11 more
TL;DR: A novel three-dimensional (3D)-printed in vitro exposure system that can be directly applied to study the effect of cannabis smoke exposure on primary human bronchial epithelial cells is developed and validated.
Journal ArticleDOI
Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions.
Alan Bell,Caroline A. MacCallum,Shari Margolese,Zach Walsh,Patrick Wright,Paul Daeninck,Enrico Mandarino,Gary Lacasse,Lauren de Freitas,Michelle St. Pierre,Lynne Belle-Isle,Marilou Gagnon,Sian Bevan,Tatiana A. Sanchez,Stephanie Arlt,James O'Hara,Michael Boivin,Cecilia T. Costiniuk +17 more
TL;DR: In this article , the authors present clinical practice guidelines to help clinicians and patients navigate appropriate CBM use in the management of chronic pain and co-occurring conditions, including sleep problems, anxiety, depression, and substance use disorders.
Journal ArticleDOI
The Green Sheep: Exploring the Perceived Risks and Benefits of Cannabis Among Young Military Members and Veterans
TL;DR: A qualitative study with EA veteran and military members with high-risk substance use found participants were receptive to using cannabis for pain ailments, mental health issues, and as an alternative to benzodiazepines, opioids, and alcohol, but acknowledged restrictions are needed to moderate cannabis use and mitigate negative outcomes.
Journal ArticleDOI
From a Symptom-Based to a Mechanism-Based Pharmacotherapeutic Treatment in Complex Regional Pain Syndrome
TL;DR: A review of the action and evidence of current and future pharmacotherapeutic options for complex regional pain syndrome (CRPS) is given in this article , where the available options are grouped in four categories by their therapeutic actions on the CRPS mechanisms, i.e. inflammation, central sensitisation, vasomotor disturbances and motor disturbances.
Posted ContentDOI
Patterns and perceptions of cannabis use with physical activity
TL;DR: Assessment of frequency, methods of ingestion, strain types, and timing (before, during or after) of cannabis use in combination with PA suggests that there is a sub-community of physically active individuals using cannabis with their PA, many who believe that cannabis use has a positive effect on their performance.
References
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Journal ArticleDOI
The PHQ-9: validity of a brief depression severity measure.
TL;DR: In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 is also a reliable and valid measure of depression severity, which makes it a useful clinical and research tool.
Book
Harrison's Principles of Internal Medicine
TL;DR: In this article, Cardinal Manifestations of Disease Genetics and Disease Clinical Pharmacology Nutrition Infectious Disease Disorders Of The Cardiovascular System Disorders Of the Kidney And Urinary Tract Disorders Of Gastrointestinal System Disorders of The Immune System, Connective Tissue And Joints Hematology And Oncology Endocrinology And Metabolism Neurologic Disorders Environmental And Occupational Hazards.
Journal ArticleDOI
Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
TL;DR: Using a standard outcome across chronic pain studies would greatly enhance the comparability, validity, and clinical applicability of these studies, and the application of these results to future studies may provide a standard definition of clinically important improvement in clinical trials of chronic pain therapies.
Journal ArticleDOI
Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage
TL;DR: Treatment needs to move from merely suppressing symptoms to a disease-modifying strategy aimed at both preventing maladaptive plasticity and reducing intrinsic risk.