Milk bioactive peptide database: A comprehensive database of milk protein-derived bioactive peptides and novel visualization
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TLDR
During processing and digestion, milk proteins are disassembled into peptides with an array of biological functions, including antimicrobial, angiotensin-converting enzyme inhibition, antioxidant, opioid, and immunomodulation, which are summarized in numerous reviews.About:
This article is published in Food Chemistry.The article was published on 2017-10-01 and is currently open access. It has received 286 citations till now.read more
Citations
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OtherDOI
Machine Learning Approaches to Improve Prediction of Target‐Drug Interactions
TL;DR: In this paper , the authors review some of the most used machine learning techniques in drug-target interactions and a special section about peptide-based drugs and its advantages over small organic molecules is discussed.
Book ChapterDOI
Bioactivity of Milk Components
TL;DR: In this article , the authors reviewed new studies on bioactive peptides in dairy products and their effects on the human body, including muscle building, reducing blood pressure, preventing tooth decay, diabetes, cancer, and many others.
Journal ArticleDOI
Effect of Fermentation with Streptococcus thermophilus Strains on In Vitro Gastro-Intestinal Digestion of Whey Protein Concentrates
TL;DR: In this article , the effect of simulated GID on three WPC hydrolysates fermented with S. thermophilus strains, as well as on unfermented WPC was studied in terms of protein hydrolysis, biological activities, and peptidomics profiles, respectively.
Book ChapterDOI
Immunomodulatory Properties of Nutraceuticals and Functional Foods
TL;DR: In this article , the authors have highlighted polyphenolic antioxidants, vitamins, probiotics, prebiotics, and peptides as immunomodulators for maintaining the immune system in proper conditions to counteract noncommunicable chronic diseases, harmful entities (toxic xenobiotics, allergens, and microbial pathogens), cancer, and emerging infectious and autoimmune diseases that currently affect health systems worldwide.
Book ChapterDOI
IntroductionFood proteomics: technological advances, current applications and future perpectives
TL;DR: In this article , the authors present the main challenges in the food industry related to the protein field. These challenges are focused on food quality and safety as well as the search of new protein biomarkers and proteomic approaches of classical issues such as allergenicity, or authentication among others.
References
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Journal ArticleDOI
Amino acid substitution matrices from protein blocks
TL;DR: This work has derived substitution matrices from about 2000 blocks of aligned sequence segments characterizing more than 500 groups of related proteins, leading to marked improvements in alignments and in searches using queries from each of the groups.
Journal ArticleDOI
Peptide Antimicrobial Agents
TL;DR: The structural requirements of peptides for antiviral and antibacterial activities are evaluated in light of the diverse set of primary and secondary structures described for host defense peptides.
Journal ArticleDOI
Peptide therapeutics: current status and future directions.
Keld Fosgerau,Torsten Hoffmann +1 more
TL;DR: The current status, strengths, and weaknesses of peptides as medicines and the emerging new opportunities in peptide drug design and development are discussed.
Journal ArticleDOI
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence.
TL;DR: Results suggest that selective binding of the COOH-terminal dipeptide residue is an impor tan t dete rminant of both the substrate specificity of angiotensin-converting enzyme and the degree of rate stimulation by chloride ion, and that the nature of this selective binding can be further clarified by studying competitive inhibition of dpeptides of vary ing structure.
Journal ArticleDOI
Bioactive Milk Peptides: A Prospectus
TL;DR: This work reviews the scientific literature and attempts to stimulate consideration of the continued use of bioactive peptides and their expanded development as a commercial product.
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