Journal ArticleDOI
Mucin-1 conjugated polyamidoamine-based nanoparticles for image-guided delivery of gefitinib to breast cancer
Poorya Najjari Nabi,Nasim Vahidfar,Mohammad Reza Tohidkia,Aliasghar Hamidi,Yadollah Omidi,Ayuob Aghanejad +5 more
TLDR
In this paper, the authors examined the impact of mucin-1 aptamer-conjugated NPs which were engineered using PAM for image-guided delivery of gefitinib (GEF) in the breast cancer cells/tumor.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2021-03-31. It has received 31 citations till now.read more
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Book ChapterDOI
Aptamers as smart ligands for the development of cancer-targeting nanocarriers
TL;DR: In this paper , the authors provide comprehensive insights into smart multifunctional Ap-armed nanomedicines and theranostics and discuss their applications in cancer diagnosis and therapy, which can be used for the delivery of genes or drugs to modify the anomalous expression of designated genes or induce cytotoxic effects on tumor cells.
Journal ArticleDOI
Radiolabeled Dendrimer Coated Nanoparticles for Radionuclide Imaging and Therapy: A Systematic Review
Miriam Conte,Maria Silvia De Feo,Marko Magdi Abdou Sidrak,Ferdinando Corica,Joana Gorica,Luca Filippi,Orazio Schillaci,Giuseppe De Vincentis,Viviana Frantellizzi +8 more
TL;DR: In this paper, a systematic review aims to summarize the development of newer dendrimers for oncological applications in nuclear medicine, and the accepted studies considered the synthesis of Dendrimer complexes for on-cological nuclear medicine imaging and therapy.
Journal ArticleDOI
Advanced nanoscale drug delivery systems for bone cancer therapy.
TL;DR: In this paper , the authors provide deep insights into the development of various DDSs applied in targeting and eradicating osteosarcoma (OS), which is the most intimidating cancer of the bone tissue, which is mostly found in the log bones in young children and older adults.
Journal ArticleDOI
Spinal Reirradiation-Mediated Myelopathy: A Systematic Review and Meta-Analysis.
Azadeh Amraee,Mohammad Reza Tohidkia,Leili Darvish,Ali Tarighatnia,Nasrin Robatmili,Atena Rahimi,Narges Rezaei,F. Ansari,Saeed Hosseini Teshnizi,Ayuob Aghanejad +9 more
TL;DR: In this article , a meta-analysis aimed to determine the safe dose in terms of biological effective dose (BED), cumulative dose and dose interval between BED1 and BED2 to decrease or prevent myelopathy and pain control in patients undergoing radiation therapy in the spinal cord.
Book ChapterDOI
Aptamer-based theranostic approaches for treatment of cancer
TL;DR: Aptamers are short synthetic single-stranded DNA or RNA oligonucleotides emerging as novel structures to target various cognate compounds such as nucleotides and proteins as mentioned in this paper .
References
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray,Jacques Ferlay,Isabelle Soerjomataram,Rebecca L. Siegel,Lindsey A. Torre,Ahmedin Jemal +5 more
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Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity
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Clinical toxicities of nanocarrier systems.
Karina R. Vega-Villa,Jody K. Takemoto,Jaime A. Yáñez,Connie M. Remsberg,M. Laird Forrest,Neal M. Davies +5 more
TL;DR: Nanocarrier may alter the physicochemical properties of xenobiotics resulting in pharmaceutical changes in stability, solubility, and pharmacokinetic disposition, and in particular, nanocarriers may reduce toxicity of hydrophobic cancer drugs that are solubilized.
Journal ArticleDOI
Recent Advances in the Treatment of Breast Cancer
TL;DR: The heterogeneity of T NBC is discussed and how molecular subtyping of TNBC may help drug discovery for this deadly disease.