Journal ArticleDOI
Multifunctional nanoparticles for upconversion luminescence/MR multimodal imaging and magnetically targeted photothermal therapy.
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TLDR
This work develops multifunctional nanoparticles (MFNPs) with highly integrated functionalities including upconversion luminescence, superparamagnetism, and strong optical absorption in the near-infrared (NIR) region with high photostability with outstanding photothermal therapeutic efficacy in a murine breast cancer model.About:
This article is published in Biomaterials.The article was published on 2012-03-01. It has received 345 citations till now. The article focuses on the topics: Photothermal therapy.read more
Citations
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Functional Nanomaterials for Phototherapies of Cancer
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Upconversion luminescent materials: advances and applications.
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Enhancing solar cell efficiency: the search for luminescent materials as spectral converters
TL;DR: This review will survey recent progress in the development of spectral converters, with a particular emphasis on lanthanide-based upconversion, quantum-cutting and down-shifting materials, for PV applications, and present technical challenges that arise in developing cost-effective high-performance solar cells based on these luminescent materials.
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Recent Progress in Rare Earth Micro/Nanocrystals: Soft Chemical Synthesis, Luminescent Properties, and Biomedical Applications
TL;DR: Synthesis, Luminescent Properties, and Biomedical Applications Shili Gai,‡ Chunxia Li,† Piaoping Yang,*,‡ and Jun Lin*,† † state Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences.
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Clinical development and potential of photothermal and photodynamic therapies for cancer
TL;DR: An overview of the current clinical progress of phototherapies for cancer and discuss the emerging preclinical bioengineering approaches that have the potential to overcome challenges in this area and thus improve the efficiency and utility of such treatments are provided.
References
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Journal ArticleDOI
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
Leon R. Hirsch,R.J. Stafford,James A. Bankson,S.R. Sershen,Belinda Rivera,Roger E. Price,John D. Hazle,Nancy J. Halas,Jennifer L. West +8 more
TL;DR: In vivo studies under magnetic resonance guidance revealed that exposure to low doses of NIR light in solid tumors treated with metal nanoshells reached average maximum temperatures capable of inducing irreversible tissue damage, and found good correlation with histological findings.
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Monodisperse MFe2O4 (M = Fe, Co, Mn) Nanoparticles
Shouheng Sun,Hao Zeng,David B. Robinson,Simone Raoux,Philip M. Rice,Shan X. Wang,Guanxiong Li +6 more
TL;DR: As-synthesized iron oxide nanoparticles have a cubic spinel structure as characterized by HRTEM, SAED, and XRD and can be transformed into hydrophilic ones by adding bipolar surfactants, and aqueous nanoparticle dispersion is readily made.
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Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy
TL;DR: This work is the first success of using carbon nanomaterials for efficient in vivo photothermal therapy by intravenous administration and suggests the great promise of graphene in biomedical applications, such as cancer treatment.
Journal ArticleDOI
Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging
TL;DR: The design parameters that affect MNP performance in vivo are summarized, including the physicochemical properties and nanoparticle surface modifications, such as MNP coating and targeting ligand functionalizations that can enhance MNP management of biological barriers.
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Tuning upconversion through energy migration in core–shell nanoparticles
Feng Wang,Renren Deng,Juan Wang,Qingxiao Wang,Yu Han,Haomiao Zhu,Xueyuan Chen,Xiaogang Liu,Xiaogang Liu +8 more
TL;DR: By rational design of a core-shell structure with a set of lanthanide ions incorporated into separated layers at precisely defined concentrations, efficient upconversion emission can be realized through gadolinium sublattice-mediated energy migration for a wide range of Lanthanide activators without long-lived intermediary energy states.
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