Journal ArticleDOI
Mycoplasma hyopneumoniae: from disease to vaccine development.
Simone Simionatto,Silvana Beutinger Marchioro,Silvana Beutinger Marchioro,Dominiek Maes,Odir Antônio Dellagostin +4 more
TLDR
In this review, the characteristics of M. hyopneumoniae related to pathogenesis and control measures will be discussed and special emphasis will be placed on vaccination strategies that have been proposed with the use of reverse vaccinology approaches.About:
This article is published in Veterinary Microbiology.The article was published on 2013-08-30. It has received 75 citations till now. The article focuses on the topics: Mycoplasma hyopneumoniae & Reverse vaccinology.read more
Citations
More filters
Journal ArticleDOI
Update on Mycoplasma hyopneumoniae infections in pigs: Knowledge gaps for improved disease control.
TL;DR: The present paper reviews the current knowledge on M. hyopneumoniae infections, with emphasis on identification and analysis of knowledge gaps for optimizing control of the disease.
Journal ArticleDOI
A review of reverse vaccinology approaches for the development of vaccines against ticks and tick borne diseases.
TL;DR: The field of reverse vaccinology developed as an outcome of the genome sequence revolution as discussed by the authors, where computers were used to mine genome sequences to rationally design recombinant vaccines, which led to the elimination of several highly infectious diseases.
Journal ArticleDOI
MIB–MIP is a mycoplasma system that captures and cleaves immunoglobulin G
Yonathan Arfi,Yonathan Arfi,Laetitia Minder,Carmelo Di Primo,Aline Le Roy,Aline Le Roy,Christine Ebel,Christine Ebel,Laurent Coquet,Stéphane Claverol,Sanjay Vashee,Joerg Jores,Joerg Jores,Alain Blanchard,Alain Blanchard,Pascal Sirand-Pugnet,Pascal Sirand-Pugnet +16 more
TL;DR: An original and complex system targeting the host immunoglobulins, playing a potentially key role in the immunity evasion by mycoplasmas is highlighted.
Journal ArticleDOI
Systemic and local immune response in pigs intradermally and intramuscularly injected with inactivated Mycoplasma hyopneumoniae vaccines.
Paolo Martelli,Roberta Saleri,Valeria Cavalli,E. De Angelis,Luca Ferrari,M. Benetti,Giulia Ferrarini,G. Merialdi,Paolo Borghetti +8 more
TL;DR: The results support that the intradermal administration of an adjuvanted bacterin induces both systemic and mucosal immune responses.
Journal ArticleDOI
Elongation Factor Thermo Unstable (EF-Tu) Moonlights as an Adhesin on the Surface of Mycoplasma hyopneumoniae by Binding to Fibronectin.
Yanfei Yu,Hongen Wang,Jia Wang,Zhixin Feng,Meng Wu,Liu Beibei,Jiuqing Xin,Qiyan Xiong,Liu Maojun,Guoqing Shao +9 more
TL;DR: This work used the virulent M. hyopneumoniae strain 168 to infect swine tracheal epithelial cells (STEC) to identify the infection-associated factors by two-dimensional electrophoresis (2-DE) and found elongation factor thermo unstable (EF-Tu) exists on the cell surface of M.hyop pneumoniae.
References
More filters
Journal ArticleDOI
Molecular Biology and Pathogenicity of Mycoplasmas
TL;DR: There is now solid genetic support for the hypothesis that mycoplasmas have evolved as a branch of gram-positive bacteria by a process of reductive evolution and developed various genetic systems providing a highly plastic set of variable surface proteins to evade the host immune system.
Journal ArticleDOI
Reverse vaccinology, a genome-based approach to vaccine development.
TL;DR: The complete genomic sequence of a human pathogen represents a new unexploited field, to be used for the design of novel vaccines and antimicrobial drugs and this approach was named "reverse vaccinology".
Journal ArticleDOI
Control of Mycoplasma hyopneumoniae infections in pigs.
TL;DR: The main effects of vaccination include less clinical symptoms, lung lesions and medication use, and improved performance, however, bacterins provide only partial protection and do not prevent colonization of the organism.
Journal ArticleDOI
Swine and Poultry Pathogens: the Complete Genome Sequences of Two Strains of Mycoplasma hyopneumoniae and a Strain of Mycoplasma synoviae
Ana Tereza Ribeiro de Vasconcelos,Henrique Bunselmeyer Ferreira,Cristiano Valim Bizarro,Sandro L. Bonatto,Marcos Oliveira de Carvalho,Paulo Marcos Pinto,Darcy F. de Almeida,Luiz Gonzaga Paula de Almeida,Almeida Rosana De,Leonardo Alves-Filho,Enedina Nogueira de Assunção,Vasco Azevedo,Maurício Reis Bogo,Marcelo M. Brigido,Marcelo Brocchi,Marcelo Brocchi,Hélio Almeida Burity,Anamaria A. Camargo,Sandro da Silva Camargo,Marta S. P. Carepo,Dirce Maria Carraro,J.C.M. Cascardo,Luiza Amaral de Castro,Gisele Cavalcanti,Gustavo Chemale,Rosane G. Collevatti,Cristina W. Cunha,Bruno Dallagiovanna,Bibiana Paula Dambrós,Odir Antônio Dellagostin,Clarissa Falcão,Fabiana Fantinatti-Garboggini,Maria Sueli Soares Felipe,Laurimar Fiorentin,Glória Regina Franco,Nara Suzy Aguiar De Freitas,Diego Frias,Thalles B. Grangeiro,Edmundo C. Grisard,Claudia Teixeira Guimarães,Mariangela Hungria,Silvia Neto Jardim,Marco Aurélio Krieger,Jomar Pereira Laurino,Lucymara Fassarella Agnez Lima,Maryellen I. Lopes,Élgion Lúcio da Silva Loreto,Humberto Maciel França Madeira,Gilson P. Manfio,Andrea Queiroz Maranhão,Christyanne T. Martinkovics,Silvia Regina Batistuzzo de Medeiros,Miguel Angêlo Martins Moreira,Márcia Neiva,Cicero Eduardo Ramalho-Neto,Marisa Fabiana Nicolás,Sergio C. Oliveira,Roger Ferreira Cury Paixão,Fábio O. Pedrosa,Sérgio D.J. Pena,Maristela Pereira,Lilian Pereira-Ferrari,Itamar Antônio Piffer,Luciano da Silva Pinto,Deise Porto Potrich,Anna Christina M. Salim,Fabrício R. Santos,Renata Schmitt,Maria Paula Cruz Schneider,Augusto Schrank,Irene Silveira Schrank,Adriana F. Schuck,Héctor N. Seuánez,Denise Wanderlei Silva,Rosane Silva,Sergio Ceroni da Silva,Célia Maria de Almeida Soares,Kelly Rose Lobo de Souza,Rangel C. Souza,Charley Christian Staats,Maria B. R. Steffens,Santuza M. R. Teixeira,Turán P. Ürményi,Marilene Henning Vainstein,Luciana W. Zuccherato,Andrew J. G. Simpson,Arnaldo Zaha +86 more
TL;DR: Genomic comparisons revealed that reduction in genome size implied loss of redundant metabolic pathways, with maintenance of alternative routes in different species, and indicated a likely transfer event of hemagglutinin-coding DNA sequences from M. gallisepticum to M. synoviae.
Journal Article
Some recommendations concerning primary isolation of Mycoplasma suipneumoniae and Mycoplasma flocculare a survey.
TL;DR: A description is given of a new medium with which primary isolation of mycoplasma species of the porcine respiratory tract is usually successful, and various additives often recommended for myCoplasma cultivation have been examined for growth promoting effect.
Related Papers (5)
Swine and Poultry Pathogens: the Complete Genome Sequences of Two Strains of Mycoplasma hyopneumoniae and a Strain of Mycoplasma synoviae
Ana Tereza Ribeiro de Vasconcelos,Henrique Bunselmeyer Ferreira,Cristiano Valim Bizarro,Sandro L. Bonatto,Marcos Oliveira de Carvalho,Paulo Marcos Pinto,Darcy F. de Almeida,Luiz Gonzaga Paula de Almeida,Almeida Rosana De,Leonardo Alves-Filho,Enedina Nogueira de Assunção,Vasco Azevedo,Maurício Reis Bogo,Marcelo M. Brigido,Marcelo Brocchi,Marcelo Brocchi,Hélio Almeida Burity,Anamaria A. Camargo,Sandro da Silva Camargo,Marta S. P. Carepo,Dirce Maria Carraro,J.C.M. Cascardo,Luiza Amaral de Castro,Gisele Cavalcanti,Gustavo Chemale,Rosane G. Collevatti,Cristina W. Cunha,Bruno Dallagiovanna,Bibiana Paula Dambrós,Odir Antônio Dellagostin,Clarissa Falcão,Fabiana Fantinatti-Garboggini,Maria Sueli Soares Felipe,Laurimar Fiorentin,Glória Regina Franco,Nara Suzy Aguiar De Freitas,Diego Frias,Thalles B. Grangeiro,Edmundo C. Grisard,Claudia Teixeira Guimarães,Mariangela Hungria,Silvia Neto Jardim,Marco Aurélio Krieger,Jomar Pereira Laurino,Lucymara Fassarella Agnez Lima,Maryellen I. Lopes,Élgion Lúcio da Silva Loreto,Humberto Maciel França Madeira,Gilson P. Manfio,Andrea Queiroz Maranhão,Christyanne T. Martinkovics,Silvia Regina Batistuzzo de Medeiros,Miguel Angêlo Martins Moreira,Márcia Neiva,Cicero Eduardo Ramalho-Neto,Marisa Fabiana Nicolás,Sergio C. Oliveira,Roger Ferreira Cury Paixão,Fábio O. Pedrosa,Sérgio D.J. Pena,Maristela Pereira,Lilian Pereira-Ferrari,Itamar Antônio Piffer,Luciano da Silva Pinto,Deise Porto Potrich,Anna Christina M. Salim,Fabrício R. Santos,Renata Schmitt,Maria Paula Cruz Schneider,Augusto Schrank,Irene Silveira Schrank,Adriana F. Schuck,Héctor N. Seuánez,Denise Wanderlei Silva,Rosane Silva,Sergio Ceroni da Silva,Célia Maria de Almeida Soares,Kelly Rose Lobo de Souza,Rangel C. Souza,Charley Christian Staats,Maria B. R. Steffens,Santuza M. R. Teixeira,Turán P. Ürményi,Marilene Henning Vainstein,Luciana W. Zuccherato,Andrew J. G. Simpson,Arnaldo Zaha +86 more