Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
TLDR
In the EU, the highest age-standardised incidence rates for oesophageal cancer are in the Netherlands for men and the UK for women, and variation between countries is high and may reflect different prevalence of risk factors, use of screening and diagnostic methods.About:
This article is published in Annals of Oncology.The article was published on 2013-10-01 and is currently open access. It has received 810 citations till now. The article focuses on the topics: European union & Cancer.read more
Citations
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Recurrence following curative intended surgery for an adenocarcinoma in the gastroesophageal junction: a retrospective study.
TL;DR: Survival was inversely associated with recurrence, but a survival comparison between local and distant recurrences showed no significant difference: median survival time was 28 months (IQR: 17-43 months) versus 24 months ( IQR: 16-36 months), P = 0.45, respectively.
Journal ArticleDOI
Single‐cell transcriptomics provides insights into the origin and microenvironment of human oesophageal high‐grade intraepithelial neoplasia
Guo-Bin Liao,Nan Dai,Tiantian Xiong,Xiang Wang,Xinwei Diao,Zhizhen Xu,Y H Ni,Ding Siok Chen,Airui Jiang,Hui Lin,Shuangshuang Dai,Jianying Bai +11 more
TL;DR: 3D Organoid experiments and RNA‐sequencing showed that basal‐cell features and the differentiation ability of the normal epithelium were largely retained in HIN, but may change dramatically in tumour invasion stage, and the tumour microenvironment of HIN was characterised by both inflammation and immunosuppression.
Journal ArticleDOI
Clinical Tumor Staging of Adenocarcinoma of the Esophagus and Esophagogastric Junction
Richard C. Turkington,Eileen Parkes,Richard D. Kennedy,Martin Eatock,Claire N. Harrison,Paula McCloskey,Colin Purcell +6 more
TL;DR: Following adjustment for known clinicopathologic variables, tumor downstaging was associated with a reduction in the risk of recurrence and death, suggesting that major clinical decisions should be based on postchemotherapy staging.
Journal ArticleDOI
Tracheal resection and anterior mediastinal tracheostomy in the multidisciplinary treatment of esophageal cancer with tracheal invasion.
Makoto Yamasaki,Kotaro Yamashita,Takuro Saito,Koji Tanaka,Tomoki Makino,Yasuhiro Miyazaki,Tsuyoshi Takahashi,Yukinori Kurokawa,Kiyokazu Nakajima,Masaaki Motoori,Yutaka Kimura,Masaki Mori,Yuichiro Doki +12 more
TL;DR: Modelling AMT safety and optimizing patient selection may improve prognosis among patients with this cancer, and response to prior treatment as an independent prognostic factor in these patients.
Journal ArticleDOI
Overexpression of cyclin-dependent kinase 1 in esophageal squamous cell carcinoma and its clinical significance
Han-Jie Zhang,Gang Chen,Shang-Wei Chen,Zong-Wang Fu,Hua-Fu Zhou,Zhen-Bo Feng,Jun-Xian Mo,Chang-Bo Li,Jun Liu +8 more
TL;DR: In this paper, the expression and clinical value of CDK1 in esophageal squamous cell carcinoma (ESCC) was analyzed using microarray and external RNA-seq data from 664 cases of ESCC and 1733 cases of control tissues.
References
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Book
AJCC Cancer Staging Manual
Mahul B. Amin,Stephen B. Edge,Frederick L. Greene,David R. Byrd,Robert K. Brookland,Mary Kay Washington,Jeffrey E. Gershenwald,Carolyn C. Compton,Kenneth R. Hess,Daniel C. Sullivan,J. Milburn Jessup,James D. Brierley,Lauri E. Gaspar,Richard L. Schilsky,Charles M. Balch,David P. Winchester,Elliot A. Asare,Martin Madera,Donna M. Gress,Laura R. Meyer +19 more
TL;DR: Purposes and Principles of Cancer Staging and End-Results Reporting are explained.
Journal ArticleDOI
Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer
David Cunningham,William H. Allum,Sally P. Stenning,Jeremy Thompson,Marianne Nicolson,J. Howard Scarffe,F. Lofts,Stephen Falk,Timothy Iveson,David Smith,Ruth E Langley,Monica Verma,Simon Weeden,Yu Jo Chua +13 more
TL;DR: In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival.
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Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
J. Ferlay,Eva Steliarova-Foucher,Joannie Lortet-Tieulent,Sonia Rosso,Jan Willem Coebergh,Harry Comber,David Forman,Freddie Bray +7 more
TL;DR: Up-to-date estimates of the cancer burden in Europe alongside the description of the varying distribution of common cancers at both the regional and country level provide a basis for establishing priorities to cancer control actions in Europe.
Journal ArticleDOI
Hospital Volume and Surgical Mortality in the United States
John D. Birkmeyer,Andrea E. Siewers,Emily Finlayson,Therese A. Stukel,F. Lee Lucas,Ida Batista,H. Gilbert Welch,David E. Wennberg +7 more
TL;DR: Mortality decreased as volume increased for all 14 types of procedures, but the relative importance of volume varied markedly according to the type of procedure.
Journal ArticleDOI
Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer
TL;DR: Preoperative chemoradiotherapy improved survival among patients with potentially curable esophageal or esophagogastric-junction cancer and the regimen was associated with acceptable adverse-event rates.
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