Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
TLDR
In the EU, the highest age-standardised incidence rates for oesophageal cancer are in the Netherlands for men and the UK for women, and variation between countries is high and may reflect different prevalence of risk factors, use of screening and diagnostic methods.About:
This article is published in Annals of Oncology.The article was published on 2013-10-01 and is currently open access. It has received 810 citations till now. The article focuses on the topics: European union & Cancer.read more
Citations
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Prognostic value of sarcopenia in patients treated by Radiochemotherapy for locally advanced oesophageal cancer.
R. Mallet,Romain Modzelewski,J. Lequesne,Sorina Dana Mihailescu,Pierre Decazes,H. Auvray,Ahmed Benyoucef,Frédéric Di Fiore,Pierre Vera,Bernard Dubray,Sébastien Thureau +10 more
TL;DR: Sarcopenia is a powerful independent prognostic factor, associated with a rise of the overall mortality in patients treated exclusively by radiochemotherapy for a locally advanced oesophageal cancer.
Journal ArticleDOI
Blocking FGFR4 exerts distinct anti-tumorigenic effects in esophageal squamous cell carcinoma.
Zhongwei Xin,Xue-Min Song,Bin Jiang,Xin Gong-Sun,Liang Song,QiMing Qin,Qiang Wang,Mo Shi,Xiangyan Liu +8 more
TL;DR: The FGFR family can be activated by FGFs and plays important roles in regulating cell growth, differentiation, migration, and angiogenesis, and the potential roles of FGFR4 in ESCC remain unknown.
Journal ArticleDOI
Benchmark values for transthoracic esophagectomy are not set as the defined "best possible"-a validation study.
TL;DR: Benchmark values assessing postoperative morbidity after MIE do not represent the defined "best achievable" results after completed learning curves, and all parameters measuring complications showed better results in this study.
Journal ArticleDOI
Neoadjuvant therapy for advanced esophageal cancer: the impact on surgical management
TL;DR: As neoadjuvant therapy is administered with the assumption that surgery will be performed, it is important for surgeons to be familiar with its impact on surgical management, and changes in treatment, according to the period and the results of up-to-date studies are discussed.
Journal ArticleDOI
Continuation versus discontinuation of first-line chemotherapy in patients with metastatic squamous cell oesophageal cancer: A randomised phase II trial (E-DIS)
Antoine Adenis,Jaafar Bennouna,P.L. Etienne,Emilie Bogart,E. Francois,M.P. Galais,M. Ben Abdelghani,Pierre Michel,J.-P. Metges,Laetitia Dahan,Thierry Conroy,François Ghiringhelli,A. Drouillard,F. El Hajbi,Emmanuelle Samalin,Sandrine Hiret,Stéphanie Delaine-Clisant,Christophe Mariette,Nicolas Penel,Guillaume Piessen,M.C. Le Deley +20 more
TL;DR: CT-CONT provides an overall survival rate that is similar to CT-DISC, and E-DIS trial provides valuable data to support shared decision-making between physicians and patients regarding CT-CONT/DISC.
References
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Book
AJCC Cancer Staging Manual
Mahul B. Amin,Stephen B. Edge,Frederick L. Greene,David R. Byrd,Robert K. Brookland,Mary Kay Washington,Jeffrey E. Gershenwald,Carolyn C. Compton,Kenneth R. Hess,Daniel C. Sullivan,J. Milburn Jessup,James D. Brierley,Lauri E. Gaspar,Richard L. Schilsky,Charles M. Balch,David P. Winchester,Elliot A. Asare,Martin Madera,Donna M. Gress,Laura R. Meyer +19 more
TL;DR: Purposes and Principles of Cancer Staging and End-Results Reporting are explained.
Journal ArticleDOI
Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer
David Cunningham,William H. Allum,Sally P. Stenning,Jeremy Thompson,Marianne Nicolson,J. Howard Scarffe,F. Lofts,Stephen Falk,Timothy Iveson,David Smith,Ruth E Langley,Monica Verma,Simon Weeden,Yu Jo Chua +13 more
TL;DR: In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival.
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Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
J. Ferlay,Eva Steliarova-Foucher,Joannie Lortet-Tieulent,Sonia Rosso,Jan Willem Coebergh,Harry Comber,David Forman,Freddie Bray +7 more
TL;DR: Up-to-date estimates of the cancer burden in Europe alongside the description of the varying distribution of common cancers at both the regional and country level provide a basis for establishing priorities to cancer control actions in Europe.
Journal ArticleDOI
Hospital Volume and Surgical Mortality in the United States
John D. Birkmeyer,Andrea E. Siewers,Emily Finlayson,Therese A. Stukel,F. Lee Lucas,Ida Batista,H. Gilbert Welch,David E. Wennberg +7 more
TL;DR: Mortality decreased as volume increased for all 14 types of procedures, but the relative importance of volume varied markedly according to the type of procedure.
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Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer
TL;DR: Preoperative chemoradiotherapy improved survival among patients with potentially curable esophageal or esophagogastric-junction cancer and the regimen was associated with acceptable adverse-event rates.
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