Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
TLDR
In the EU, the highest age-standardised incidence rates for oesophageal cancer are in the Netherlands for men and the UK for women, and variation between countries is high and may reflect different prevalence of risk factors, use of screening and diagnostic methods.About:
This article is published in Annals of Oncology.The article was published on 2013-10-01 and is currently open access. It has received 810 citations till now. The article focuses on the topics: European union & Cancer.read more
Citations
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Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial
Ken Kato,Byoung Chul Cho,Masanobu Takahashi,Morihito Okada,Chen Yuan Lin,Keisho Chin,Shigenori Kadowaki,Myung-Ju Ahn,Yasuo Hamamoto,Yuichiro Doki,Chueh Chuan Yen,Yutaro Kubota,Sung Bae Kim,Chih-Hung Hsu,Eva Holtved,Ioannis Xynos,Mamoru Kodani,Yuko Kitagawa +17 more
TL;DR: Overall survival was significantly improved in the nivolumab group compared with the chemotherapy group, and a favourable safety profile compared with chemotherapy in previously treated advanced oesophageal squamous cell carcinoma patients.
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Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Hong Yang,Hui Liu,Yuping Chen,Chengchu Zhu,Wentao Fang,Zhentao Yu,Weimin Mao,Jiaqing Xiang,Yongtao Han,Zhijian Chen,Haihua Yang,Jiaming Wang,Qingsong Pang,Xiao Zheng,Huanjun Yang,Tao Li,Florian Lordick,Xavier B. D’Journo,Robert J. Cerfolio,Robert J. Korst,Nuria M. Novoa,Scott J. Swanson,Alessandro Brunelli,Mahmoud Ismail,Hiran C. Fernando,Xu Zhang,Qun Li,Geng Wang,Baofu Chen,Teng Mao,Min Kong,Xufeng Guo,Ting Lin,Mengzhong Liu,Jianhua Fu +34 more
TL;DR: This trial shows that NCRT plus surgery improves survival over surgery alone among patients with locally advanced ESCC, with acceptable and manageable adverse events.
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Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): final results of a randomised, phase 2/3 trial
Thierry Conroy,Marie-Pierre Galais,Jean-Luc Raoul,Olivier Bouché,Sophie Gourgou-Bourgade,Jean-Yves Douillard,Pierre-Luc Etienne,Valérie Boige,Isabelle Martel-Lafay,Pierre Michel,Carmen Llacer-Moscardo,Eric Francois,Gilles Créhange,Meher Ben Abdelghani,Beata Juzyna,Laurent Bedenne,Antoine Adenis +16 more
TL;DR: The PRODIGE5/ACCORD17 trial aimed to assess the efficacy and safety of the FOLFOX treatment regimen versus fluorouracil and cisplatin as part of chemoradiotherapy in patients with localised oesophageal cancer.
Journal ArticleDOI
Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma
TL;DR: In this paper , the authors compared first-line chemotherapy for advanced esophageal squamous-cell carcinoma with the monoclonal antibody nivolumab plus chemotherapy.
Journal ArticleDOI
Indications, results, and clinical impact of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline - Updated January 2017.
Jean-Marc Dumonceau,Pierre Henri Deprez,Christian Jenssen,Julio Iglesias-Garcia,Alberto Larghi,Geoffroy Vanbiervliet,Guruprasad P. Aithal,Paolo Giorgio Arcidiacono,Pedro Bastos,Silvia Carrara,László Czakó,Gloria Fernández-Esparrach,Paul Fockens,Angels Ginès,Roald Flesland Havre,Cesare Hassan,Peter Vilmann,Jeanin E. van Hooft,Marcin Polkowski +18 more
TL;DR: ESGE suggests performing EUS-guided sampling for the assessment of regional lymph nodes in T1 (and, depending on local treatment policy, T2) adenocarcinoma and of lesions suspicious for metastasis such as distant LNs, left liver lobe lesions, and suspected peritoneal carcinomatosis.
References
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Visceral abdominal obesity measured by CT scan is associated with an increased risk of Barrett's oesophagus: a case-control study
Hashem B. El-Serag,Ali A Hashmi,Jose M. Garcia,Peter Richardson,Abeer Alsarraj,Stephanie Fitzgerald,Marcelo F. Vela,Yasser H. Shaib,Neena S. Abraham,Maria E. Velez,Rhonda A. Cole,Margot Rodriguez,Bhupinderjit S. Anand,David Y. Graham,Jennifer R. Kramer +14 more
TL;DR: Large amount of visceral abdominal fat relative to subcutaneous fat is associated with a significant increase in the risk of Barrett's oesophagus, and GERD may mediate some but not all of this association.
Journal ArticleDOI
Increased incidence and survival for oesophageal cancer but not for gastric cardia cancer in the Netherlands
Johan L. Dikken,Johan L. Dikken,Valery E.P.P. Lemmens,Michel W.J.M. Wouters,Bas P. L. Wijnhoven,Peter D. Siersema,Grard A. P. Nieuwenhuijzen,Johanna W. van Sandick,Annemieke Cats,Marcel Verheij,Jan Willem Coebergh,Cornelis J.H. van de Velde +11 more
TL;DR: The increased survival for oesophageal carcinoma can be attributed to centralisation of surgery, and an increased use of multimodality therapy, factors hardly acknowledged for gastric cancer.
Journal ArticleDOI
Prospective Comparison of Surgery Alone and Chemoradiotherapy With Selective Surgery in Resectable Squamous Cell Carcinoma of the Esophagus
Hisanori Ariga,Kenji Nemoto,Shukichi Miyazaki,Takashi Yoshioka,Yohishiro Ogawa,Toru Sakayauchi,Keiichi Jingu,Go Miyata,Ko Onodera,Hirofumi Ichikawa,Takashi Kamei,Shunsuke Kato,Chikashi Ishioka,Susumu Satomi,Shogo Yamada +14 more
TL;DR: Treatment outcomes among patients with resectable thoracic esophageal squamous cell carcinoma were comparable or superior after CRT (with salvage therapy if needed) to outcomes after surgery alone.
Journal ArticleDOI
International survey on esophageal cancer: part I surgical techniques.
TL;DR: The aims of the present study were to gain insight into the frequencies of the various surgical techniques in esophageal cancer surgery as applied by surgeons throughout the world and to identify intercontinental differences regarding surgical techniques.
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