Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
TLDR
In the EU, the highest age-standardised incidence rates for oesophageal cancer are in the Netherlands for men and the UK for women, and variation between countries is high and may reflect different prevalence of risk factors, use of screening and diagnostic methods.About:
This article is published in Annals of Oncology.The article was published on 2013-10-01 and is currently open access. It has received 810 citations till now. The article focuses on the topics: European union & Cancer.read more
Citations
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Deep‐learning‐based classification of desmoplastic reaction on H&E predicts poor prognosis in oesophageal squamous cell carcinoma
Keita Kouzu,Ines P. Nearchou,Yoshiki Kajiwara,Hironori Tsujimoto,Katherine Lillard,Yoji Kishi,Hideki Ueno +6 more
TL;DR: The prognostic significance of the deep‐learning classifier was assessed and it was compared to that of manual DR reporting and other pathological factors currently used in the clinic.
Journal ArticleDOI
External Validation of the Dutch SOURCE Survival Prediction Model in Belgian Metastatic Oesophageal and Gastric Cancer Patients
J. J. van Kleef,H. G. van den Boorn,Rob H.A. Verhoeven,K. Vanschoenbeek,Ameen Abu-Hanna,Aeilko H. Zwinderman,Mirjam A. G. Sprangers,M. G. H. van Oijen,H. De Schutter,H.W.M. van Laarhoven +9 more
TL;DR: The SOURCE gastric cancer model was well calibrated and had a similar performance in the Belgian cohort compared with the Dutch internal validation, however, the oesophageal cancer model had not.
Journal ArticleDOI
Basaloid squamous cell carcinoma: a rare tumor at the esophagogastric junction and an unexpected durable complete response to FOLFOX-4.
Chiara Alessandra Cella,Chiara Carlomagno,Florian Lordick,Roberto Moretto,Alfonso De Stefano,Lucia Raimondo,Maria D'Armiento,Luigi Camera,Elia Guadagno,Laura Attademo,Salvatore Feliciano,Elide Matano +11 more
TL;DR: The presented case illustrates the diagnostic challenges associated with BSCC of the esophagus and reports an unexpected chemosensitivity of this histotype to the combination of a platinum salt plus 5-fluorouracil which could represent an optimal treatment strategy in unfit patients.
Journal ArticleDOI
Long-Term Outcome After Histopathological Complete Response with and Without Nodal Metastases Following Multimodal Treatment of Esophageal Cancer
Wolfgang Schroeder,M. Ghadimi,Hans Anton Schloesser,Heike Loeser,Petra Schiller,Thomas Zander,Florian Gebauer,Hans F. Fuchs,Alexander Quaas,Christiane J. Bruns +9 more
TL;DR: Follow-up recommendations may be adopted in patients with pCR but outcome significantly deteriorates with the presence of nodal metastases, and “watch-and-wait” surveillance strategies with suspected clinical complete response have to be considered with caution.
Journal ArticleDOI
Automated clinical decision support system with deep learning dose prediction and NTCP models to evaluate treatment complications in patients with esophageal cancer.
C. Draguet,Ana M. Barragan-Montero,Macarena Chocan Vera,Melissa L. Thomas,Pieter Populaire,Gilles Defraene,Karin Haustermans,John Aldo Lee,Edmond Sterpin +8 more
TL;DR: In this paper , two U-Net models for photon (XT) and proton (PT) plans, respectively, were created, for estimating the dose distribution for each patient, they were trained on a database of 40 uniformly planned patients using cross validation and a circulating test set.
References
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AJCC Cancer Staging Manual
Mahul B. Amin,Stephen B. Edge,Frederick L. Greene,David R. Byrd,Robert K. Brookland,Mary Kay Washington,Jeffrey E. Gershenwald,Carolyn C. Compton,Kenneth R. Hess,Daniel C. Sullivan,J. Milburn Jessup,James D. Brierley,Lauri E. Gaspar,Richard L. Schilsky,Charles M. Balch,David P. Winchester,Elliot A. Asare,Martin Madera,Donna M. Gress,Laura R. Meyer +19 more
TL;DR: Purposes and Principles of Cancer Staging and End-Results Reporting are explained.
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Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer
David Cunningham,William H. Allum,Sally P. Stenning,Jeremy Thompson,Marianne Nicolson,J. Howard Scarffe,F. Lofts,Stephen Falk,Timothy Iveson,David Smith,Ruth E Langley,Monica Verma,Simon Weeden,Yu Jo Chua +13 more
TL;DR: In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival.
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Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
J. Ferlay,Eva Steliarova-Foucher,Joannie Lortet-Tieulent,Sonia Rosso,Jan Willem Coebergh,Harry Comber,David Forman,Freddie Bray +7 more
TL;DR: Up-to-date estimates of the cancer burden in Europe alongside the description of the varying distribution of common cancers at both the regional and country level provide a basis for establishing priorities to cancer control actions in Europe.
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Hospital Volume and Surgical Mortality in the United States
John D. Birkmeyer,Andrea E. Siewers,Emily Finlayson,Therese A. Stukel,F. Lee Lucas,Ida Batista,H. Gilbert Welch,David E. Wennberg +7 more
TL;DR: Mortality decreased as volume increased for all 14 types of procedures, but the relative importance of volume varied markedly according to the type of procedure.
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Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer
TL;DR: Preoperative chemoradiotherapy improved survival among patients with potentially curable esophageal or esophagogastric-junction cancer and the regimen was associated with acceptable adverse-event rates.
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