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Open AccessJournal ArticleDOI

Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

TLDR
In the EU, the highest age-standardised incidence rates for oesophageal cancer are in the Netherlands for men and the UK for women, and variation between countries is high and may reflect different prevalence of risk factors, use of screening and diagnostic methods.
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This article is published in Annals of Oncology.The article was published on 2013-10-01 and is currently open access. It has received 810 citations till now. The article focuses on the topics: European union & Cancer.

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The need for enhanced psychological support in esophageal cancer-an exploratory study of the perception of HCPs, patients, and carers.

TL;DR: There is an impetus to develop detailed care pathways to facilitate meeting this prioritized support need and a number of patient/carer barriers to engaging with support were identified in addition to HCP barriers.
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Metastasectomy or Stereotactic Body Radiation Therapy With or Without Systemic Therapy for Oligometastatic Esophagogastric Cancer

TL;DR: In this paper , a single-center, retrospective cohort study was conducted to determine overall survival (OS) in patients who underwent local treatment (metastasectomy or stereotactic body radiotherapy [SBRT]) or systemic therapy (chemotherapy or targeted therapy) for oligometastatic esophagogastric cancer.
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Clinical Outcome of Additional Esophagectomy After Endoscopic Treatment for Superficial Esophageal Cancer

TL;DR: In this paper, the authors evaluated the outcome of additional therapy after endoscopic treatment and found that esophagectomy rather than chemoradiotherapy (CRT) was more effective than CRT for patients with massive submucosal tumor invasion due to the risk of recurrence after CRT.
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The Oncogene AF1Q is Associated with WNT and STAT Signaling and Offers a Novel Independent Prognostic Marker in Patients with Resectable Esophageal Cancer

TL;DR: Testing AF1q could facilitate prognosis estimation and provide a possibility of identifying the patients responsive to the therapeutic blockade of its oncogenic downstream targets.
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Multimodality treatment of operable gastric and oesophageal adenocarcinoma: evaluating neoadjuvant, adjuvant and perioperative approaches.

TL;DR: This review will critically appraise the evidence base underpinning the main treatment approaches in operable oesophagogastric adenocarcinoma, highlighting variations in treatment by factors such as geographical area and primary tumor site.
References
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Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer

TL;DR: In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival.
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Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012

TL;DR: Up-to-date estimates of the cancer burden in Europe alongside the description of the varying distribution of common cancers at both the regional and country level provide a basis for establishing priorities to cancer control actions in Europe.
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Hospital Volume and Surgical Mortality in the United States

TL;DR: Mortality decreased as volume increased for all 14 types of procedures, but the relative importance of volume varied markedly according to the type of procedure.
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Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer

TL;DR: Preoperative chemoradiotherapy improved survival among patients with potentially curable esophageal or esophagogastric-junction cancer and the regimen was associated with acceptable adverse-event rates.
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