Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
TLDR
In the EU, the highest age-standardised incidence rates for oesophageal cancer are in the Netherlands for men and the UK for women, and variation between countries is high and may reflect different prevalence of risk factors, use of screening and diagnostic methods.About:
This article is published in Annals of Oncology.The article was published on 2013-10-01 and is currently open access. It has received 810 citations till now. The article focuses on the topics: European union & Cancer.read more
Citations
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Lymphovascular Invasion Increases the Risk of Nodal and Distant Recurrence in Node-Negative Stage I-IIA Non-Small-Cell Lung Cancer.
Soo Yoon Sung,Yoo-Kang Kwak,Sea-Won Lee,In Young Jo,Jae Kil Park,Kyung Soo Kim,Kyo Young Lee,Yeon-Sil Kim +7 more
TL;DR: The presence of LVI significantly increases the risk of nodal and distant recurrence and is a negative prognostic factor in patients with stage I–IIA NSCLC.
Journal ArticleDOI
Functional and cognitive impairment, social functioning, frailty and adverse health outcomes in older patients with esophageal cancer, a systematic review
Floor J. van Deudekom,Henk G. Klop,Henk H. Hartgrink,Jurjen J. Boonstra,I.M. Lips,Marije Slingerland,Simon P. Mooijaart +6 more
TL;DR: Functional and cognitive impairment, depression and social isolation are prevalent in patients with esophageal cancer, and associate with adverse health outcomes, but more large studies are needed to explore the clinical usability.
Journal ArticleDOI
Pembrolizumab for the treatment of esophageal cancer
Shun Yamamoto,Ken Kato +1 more
TL;DR: Pembrolizumab monotherapy shows a significant survival benefit in metastatic or recurrent EC patients with PD-L1 CPS ≥10 as second-line treatment and is one of the standard treatment agents for second-lined esophageal squamous cell carcinoma patients.
Journal ArticleDOI
Health-related quality of life results from the PRODIGE 5/ACCORD 17 randomised trial of FOLFOX versus fluorouracil-cisplatin regimen in oesophageal cancer.
C. Bascoul-Mollevi,Sophie Gourgou,M.P. Galais,Jean-Luc Raoul,O. Bouche,J.-Y. Douillard,Antoine Adenis,P.L. Etienne,Beata Juzyna,Laurent Bedenne,Thierry Conroy +10 more
TL;DR: Analyses of HRQOL scores revealed no statistically significant differences between patients with inoperable non-metastatic oesophageal cancer treated by FOLFOX versus those treated with a fluorouracil-cisplatin regimen as part of definitive CRT.
Journal ArticleDOI
Increased assessment of HER2 in metastatic gastroesophageal cancer patients: a nationwide population-based cohort study
Willemieke P M Dijksterhuis,Rob H.A. Verhoeven,Sybren L. Meijer,Marije Slingerland,Nadia Haj Mohammad,Judith de Vos-Geelen,Laurens V. Beerepoot,Theo van Voorthuizen,Geert-Jan Creemers,Martijn G.H. van Oijen,Hanneke W. M. van Laarhoven +10 more
TL;DR: Increased determination of HER2 and administration of trastuzumab have changed daily practice management of metastatic gastroesophageal cancer patients receiving palliative systemic therapy, and possibly contributed to their improved survival.
References
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Book
AJCC Cancer Staging Manual
Mahul B. Amin,Stephen B. Edge,Frederick L. Greene,David R. Byrd,Robert K. Brookland,Mary Kay Washington,Jeffrey E. Gershenwald,Carolyn C. Compton,Kenneth R. Hess,Daniel C. Sullivan,J. Milburn Jessup,James D. Brierley,Lauri E. Gaspar,Richard L. Schilsky,Charles M. Balch,David P. Winchester,Elliot A. Asare,Martin Madera,Donna M. Gress,Laura R. Meyer +19 more
TL;DR: Purposes and Principles of Cancer Staging and End-Results Reporting are explained.
Journal ArticleDOI
Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer
David Cunningham,William H. Allum,Sally P. Stenning,Jeremy Thompson,Marianne Nicolson,J. Howard Scarffe,F. Lofts,Stephen Falk,Timothy Iveson,David Smith,Ruth E Langley,Monica Verma,Simon Weeden,Yu Jo Chua +13 more
TL;DR: In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival.
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Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
J. Ferlay,Eva Steliarova-Foucher,Joannie Lortet-Tieulent,Sonia Rosso,Jan Willem Coebergh,Harry Comber,David Forman,Freddie Bray +7 more
TL;DR: Up-to-date estimates of the cancer burden in Europe alongside the description of the varying distribution of common cancers at both the regional and country level provide a basis for establishing priorities to cancer control actions in Europe.
Journal ArticleDOI
Hospital Volume and Surgical Mortality in the United States
John D. Birkmeyer,Andrea E. Siewers,Emily Finlayson,Therese A. Stukel,F. Lee Lucas,Ida Batista,H. Gilbert Welch,David E. Wennberg +7 more
TL;DR: Mortality decreased as volume increased for all 14 types of procedures, but the relative importance of volume varied markedly according to the type of procedure.
Journal ArticleDOI
Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer
TL;DR: Preoperative chemoradiotherapy improved survival among patients with potentially curable esophageal or esophagogastric-junction cancer and the regimen was associated with acceptable adverse-event rates.
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