Orexin A excites the rat olivary pretectal nucleus via OX2 receptor in a daily manner.
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TLDR
In this paper, the olivary pretectal nucleus (OPN) was found to be a retinorecipient structure primarily involved in the pupillary light reflex.About:
This article is published in Brain Research.The article was published on 2021-05-13 and is currently open access. It has received 4 citations till now. The article focuses on the topics: Orexin-A & Orexin.read more
Citations
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Journal ArticleDOI
Daily coordination of orexinergic gating in the rat superior colliculus—Implications for intrinsic clock activities in the visual system
Lukasz Chrobok,Jagoda Stanislawa Jeczmien-Lazur,Monika Bubka,Kamil Pradel,Aleksandra Klekocinska,Jasmin Daniela Klich,Amalia Ridla Rahim,Jihwan Myung,Mariusz Kepczynski,Marian H. Lewandowski +9 more
TL;DR: In this paper, a combination of electrophysiological, immunohistochemical, and molecular approaches across 24 hours was used to investigate the daily coordination between the orexin system and the superior colliculus (SC).
Journal ArticleDOI
From Fast Oscillations to Circadian Rhythms: Coupling at Multiscale Frequency Bands in the Rodent Subcortical Visual System
TL;DR: The subcortical visual system (SVS) is a unique collection of brain structures localised in the thalamus, hypothalamus and midbrain this article, which receives ambient light inputs from retinal ganglion cells and integrates this signal with internal homeostatic demands to influence physiology.
Journal ArticleDOI
Control and coding of pupil size by hypothalamic orexin neurons
TL;DR: In this paper , cell-specific stimulation, deletion and in vivo recordings revealed strong correlative and causal links between pupil dilation and orexin cell activity, indicating that they specialize in rapid, multiplexed communication of momentary arousal and reward states.
Journal ArticleDOI
Metabolic cues impact non‐oscillatory intergeniculate leaflet and ventral lateral geniculate nucleus: standard versus high‐fat diet comparative study
TL;DR: In this article , the effect of metabolically relevant peptides on the spontaneous activity of IGL/VLG neurons was investigated using ex vivo and in vivo electrophysiological recordings as well as in situ hybridisation.
References
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Journal ArticleDOI
Circadian regulation of mouse suprachiasmatic nuclei neuronal states shapes responses to orexin.
Mino D. C. Belle,Hugh D. Piggins +1 more
TL;DR: How the resting state of SCN neurons determines their response to OXA is demonstrated, and the inhibitory action of this neurochemical correlate of arousal can trigger paradoxical AP firing is illustrated.
Journal ArticleDOI
Multiple excitatory actions of orexins upon thalamo-cortical neurons in dorsal lateral geniculate nucleus - implications for vision modulation by arousal.
Lukasz Chrobok,Katarzyna Palus-Chramiec,Anna Chrzanowska,Mariusz Kepczynski,Marian H. Lewandowski +4 more
TL;DR: It is hypothesised that the depolarising effects of orexins upon DLG neurons may facilitate signal transmission through the visual thalamo-cortical pathway during behavioural arousal, and underlie the circadian/behavioural modulation of vision.
Journal ArticleDOI
PAC1- and VPAC2 receptors in light regulated behavior and physiology: Studies in single and double mutant mice
TL;DR: The data demonstrate that in although being closely related at both ligand and receptor structure/sequence, PACAP/PAC1 receptor signaling are independent of VIP/VPAC2 receptor signaling and vice versa, and lack of either of the receptors does not result in compensatory changes at neither the physiological or anatomical level.
Journal ArticleDOI
Circadian actions of orexins on the retinorecipient lateral geniculate complex in rat
Lukasz Chrobok,Jagoda Stanislawa Jeczmien-Lazur,Kamil Pradel,Jasmin Daniela Klich,Monika Bubka,Michal Wojcik,Mariusz Kepczynski,Marian H. Lewandowski +7 more
TL;DR: It is shown that orexins exert an excitatory action in three parts of the lateral geniculate nucleus (LGN), in particular upon directly retinorecipient neurons in the non‐image forming visual structures, helping to better understand circadian orexinergic control over the non-image forming subcortical visual system.
Book ChapterDOI
Perforated Multi-Electrode Array Recording in Hypothalamic Brain Slices.
TL;DR: An overview of a step-by-step method to perform multisite extracellular AP activity recordings in suprachiasmatic and mediobasal hypothalamic nuclei brain slices, using a state-of-the-art perforated multielectrode array system.