Journal ArticleDOI
Paediatric cancer in low-income and middle-income countries
Ian Magrath,Eva Steliarova-Foucher,Sidnei Epelman,Raul C. Ribeiro,Mhamed Harif,Chi Kong Li,Rejin Kebudi,Scott D Macfarlane,Scott C. Howard +8 more
TLDR
This work discusses childhood cancer in relation to global development and proposes strategies that could result in improved survival and education of the public, more and better-trained health professionals, strengthened cancer services, locally relevant research, regional hospital networks, international collaboration, and health insurance are all essential components of an enhanced model of care.Abstract:
Summary Patterns of cancer incidence across the world have undergone substantial changes as a result of industrialisation and economic development. However, the economies of most countries remain at an early or intermediate stage of development—these stages are characterised by poverty, too few health-care providers, weak health systems, and poor access to education, modern technology, and health care because of scattered rural populations. Low-income and middle-income countries also have younger populations and therefore a larger proportion of children with cancer than high-income countries. Most of these children die from the disease. Chronic infections, which remain the most common causes of disease-related death in all except high-income countries, can also be major risk factors for childhood cancer in poorer regions. We discuss childhood cancer in relation to global development and propose strategies that could result in improved survival. Education of the public, more and better-trained health professionals, strengthened cancer services, locally relevant research, regional hospital networks, international collaboration, and health insurance are all essential components of an enhanced model of care.read more
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Outcomes of children with rhabdomyosarcoma treated with intensive chemotherapy, surgery, and radiotherapy through a period of protocol revision at a South African center, 1990-2010
Marc Hendricks,Jeanette Parkes,Komala Pillay,Alastair J. W. Millar,Ann van Eyssen,Alp Numanoglu,Alan Davidson +6 more
TL;DR: There was a trend to suggest that revision of treatment approaches improved crude survival over time: pre‐2003 (OS 42.1%); 2003–2005 (OS 50.0%); 2005–2010 (OS 60.8%).
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Stakeholder collaboration: Government, private sector and non-governmental organizations can build pediatric oncology services in India
Shruti Kakkar,Vaneet Anand,Mani Mahajan,P. Sandhu,Manjit Kaur Rana,Karuna Singh,Amandeep Kaur,Inderjit Kaur,Alka Jindal,Haresh Gupta,Poonam Bagai +10 more
Journal ArticleDOI
Management of Children with Wilms Tumor in Africa and Europe; Thoughts About Costs, Priorities and Collaboration
Trijn Israels,Simon Bailey,R. Verschoor,Gertjan J.L. Kaspers,Neil Kennedy,Elizabeth Molyneux +5 more
TL;DR: This paper aims to provide a history of paediatric oncology in Malawi and some of the techniques and practices used in the treatment of childhood cancer.
Journal ArticleDOI
Clinical Profile of Pediatric Oncology Patients Treated by External Beam Radiotherapy: An Institutional Experience.
TL;DR: The clinical profile of pediatric cancer patients who received radiation, either alone or as adjuvant to surgery and chemotherapy; in prophylactic, radical or palliative clinical setting is presented.
Journal ArticleDOI
Birth weight and risk of childhood solid tumors in Brazil: a record linkage between population-based data sets.
Neimar de Paula Silva,Rejane de Souza Reis,Rafael Garcia Cunha,Julio Fernando Pinto Oliveira,Fernanda Cristina da Silva de Lima,Maria S. Pombo-de-Oliveira,Marceli de Oliveira Santos,Beatriz de Camargo +7 more
TL;DR: Increased birth weight was associated with childhood solid tumor development, especially among children more than 3 years old with “miscellaneous” tumors, and among children diagnosed after reaching the age of 3 years, the OR was significantly increased.
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