Journal ArticleDOI
Paediatric cancer in low-income and middle-income countries
Ian Magrath,Eva Steliarova-Foucher,Sidnei Epelman,Raul C. Ribeiro,Mhamed Harif,Chi Kong Li,Rejin Kebudi,Scott D Macfarlane,Scott C. Howard +8 more
TLDR
This work discusses childhood cancer in relation to global development and proposes strategies that could result in improved survival and education of the public, more and better-trained health professionals, strengthened cancer services, locally relevant research, regional hospital networks, international collaboration, and health insurance are all essential components of an enhanced model of care.Abstract:
Summary Patterns of cancer incidence across the world have undergone substantial changes as a result of industrialisation and economic development. However, the economies of most countries remain at an early or intermediate stage of development—these stages are characterised by poverty, too few health-care providers, weak health systems, and poor access to education, modern technology, and health care because of scattered rural populations. Low-income and middle-income countries also have younger populations and therefore a larger proportion of children with cancer than high-income countries. Most of these children die from the disease. Chronic infections, which remain the most common causes of disease-related death in all except high-income countries, can also be major risk factors for childhood cancer in poorer regions. We discuss childhood cancer in relation to global development and propose strategies that could result in improved survival. Education of the public, more and better-trained health professionals, strengthened cancer services, locally relevant research, regional hospital networks, international collaboration, and health insurance are all essential components of an enhanced model of care.read more
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Journal ArticleDOI
Pediatric lymphoma patients in Malawi present with poor health-related quality of life at diagnosis and improve throughout treatment and follow-up across all Pediatric PROMIS-25 domains.
Grace K. Ellis,Hutton Chapman,Agness Manda,Ande Salima,Salama Itimu,Grace Banda,Ryan Seguin,Geoffrey Manda,Mercy Butia,Minke Huibers,Nmazuo W. Ozuah,Alyssa E. Tilly,Angela M. Stover,Ethan Basch,Satish Gopal,Bryce B. Reeve,Katherine D. Westmoreland +16 more
TL;DR: In this paper, the Chichewa Pediatric Patient-Reported Outcome Measurement Information System Pediatric (PROMIS)-25 at diagnosis, active treatment, and follow-up among pediatric lymphoma patients in Lilongwe, Malawi.
Journal ArticleDOI
Palliative Care in Paediatric Oncology: an Update
TL;DR: Palliative care referral in children with cancer improves physical symptoms, emotional support, and quality of life, and facilitates less invasive diagnostic and therapeutic interventions at the end of life as mentioned in this paper .
Journal ArticleDOI
Impact of the COVID-19 pandemic on paediatric patients with cancer in low-income, middle-income and high-income countries: protocol for a multicentre, international, observational cohort study.
TL;DR: In this article, a multicentre, international cohort study was conducted to determine the variation in paediatric cancer management during the COVID-19 pandemic, and the short-term to medium-term impacts on childhood cancer outcomes.
Journal ArticleDOI
Childhood cancer: incidence and spatial patterns in the city of Campinas, Brazil, 1996-2005.
Jane Kelly Oliveira Friestino,Denisa Mendonça,Pedro Oliveira,Carla Oliveira,Djalma de Carvalho Moreira Filho +4 more
TL;DR: Analysis of cancer incidence and spatial patterns in children and adolescents residing in the city of Campinas in Southeastern Brazil who were diagnosed from 1996-2005 found no statistically significant differences in the relative risks were observed.
Book ChapterDOI
Therapy of Cancer and Retroviral Diseases
TL;DR: Dramatic advances in drug and HT developments that are expanding the spectrum of curable cancers are also associated with skyrocketing HC costs and its unaffordability, even in the wealthiest nations (WN), thus, highlighting the global need for wise choices.
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Journal ArticleDOI
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