Journal ArticleDOI
Paediatric cancer in low-income and middle-income countries
Ian Magrath,Eva Steliarova-Foucher,Sidnei Epelman,Raul C. Ribeiro,Mhamed Harif,Chi Kong Li,Rejin Kebudi,Scott D Macfarlane,Scott C. Howard +8 more
TLDR
This work discusses childhood cancer in relation to global development and proposes strategies that could result in improved survival and education of the public, more and better-trained health professionals, strengthened cancer services, locally relevant research, regional hospital networks, international collaboration, and health insurance are all essential components of an enhanced model of care.Abstract:
Summary Patterns of cancer incidence across the world have undergone substantial changes as a result of industrialisation and economic development. However, the economies of most countries remain at an early or intermediate stage of development—these stages are characterised by poverty, too few health-care providers, weak health systems, and poor access to education, modern technology, and health care because of scattered rural populations. Low-income and middle-income countries also have younger populations and therefore a larger proportion of children with cancer than high-income countries. Most of these children die from the disease. Chronic infections, which remain the most common causes of disease-related death in all except high-income countries, can also be major risk factors for childhood cancer in poorer regions. We discuss childhood cancer in relation to global development and propose strategies that could result in improved survival. Education of the public, more and better-trained health professionals, strengthened cancer services, locally relevant research, regional hospital networks, international collaboration, and health insurance are all essential components of an enhanced model of care.read more
Citations
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Journal ArticleDOI
Biomarkers and Corresponding Biosensors for Childhood Cancer Diagnostics
TL;DR: In this article , the authors provide an overview of important biomarkers for several common childhood cancers and enumerated the developed biosensors for early detection of pediatric cancer or related biomarkers.
Journal ArticleDOI
Accessibility of essential anticancer medicines for children in the Sichuan Province of China
TL;DR: In this article , the availability, price, and affordability of surveyed medicines were evaluated in all 152 tertiary public hospitals (120 general hospitals, 31 children's hospitals, and one cancer hospital) that could diagnose and treat cancer for children.
Journal ArticleDOI
Underexpression of LINC00173 in TCF3/PBX1-Positive Cases Is Associated With Poor Prognosis in Children With B-Cell Precursor Acute Lymphoblastic Leukemia
Didier Ismael May-Hau,Diego Alberto Bárcenas-López,Juan Carlos Núñez-Enríquez,Vilma Carolina Bekker-Méndez,Fredy Omar Beltrán-Anaya,Elva Jiménez-Hernández,M. Ortíz-Maganda,Francisco Xavier Guerra-Castillo,Aurora Medina-Sanson,Janet Flores-Lujano,Jorge Alfonso Martín-Trejo,José Gabriel Peñaloza-González,Martha Margarita Velázquez-Aviña,José Refugio Torres-Nava,Gabriela Alicia Hernández-Echáurregui,Rosa Martha Espinosa-Elizondo,María de Lourdes Gutiérrez-Rivera,Rodrigo Sanchez-Hernandez,María Luisa Pérez-Saldivar,Luz Victoria Flores-Villegas,Laura Elizabeth Merino-Pasaye,David Aldebarán Duarte-Rodríguez,Minerva Mata-Rocha,Omar Alejandro Sepúlveda-Robles,Haydeé Rosas-Vargas,Alfredo Hidalgo-Miranda,Juan Manuel Mejía-Aranguré,Silvia Jiménez-Morales +27 more
TL;DR: An association between the expression of LINC00173 and TCF 3/PBX1 and the risk to relapse and die in BCP-ALL, which is worse in TCF3/ PBX1-positive cases displaying underexpression of Linc00173 is observed.
Book ChapterDOI
Pediatric Neuro-Oncology in Low-/Middle-Income Countries
TL;DR: In this chapter, an illustration of the obstacles faced by LMIC neuro-oncologists will be discussed and different ways and procedures are recommended to improve the general situation to attain good results similar to that in HICs.
Journal ArticleDOI
Trends in childhood cancer incidence in sub-Saharan Africa: Results from 25 years of cancer registration in Harare (Zimbabwe) and Kyadondo (Uganda)
Ole Stoeter,Tobias Paul Seraphin,Tobias Paul Seraphin,Inam Chitsike,Eric Chokunonga,Joyce Balagadde Kambugu,Henry Wabinga,Donald Maxwell Parkin,Donald Maxwell Parkin,Eva Johanna Kantelhardt +9 more
TL;DR: In this paper, the authors examined trends in childhood cancer incidence in sub-Saharan Africa using data from two population-based cancer registries in Harare (Zimbabwe) and Kyadondo (Uganda) with cases classified according to the International Classification of Childhood Cancer and explored reasons for observed variations and changes.
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