Journal ArticleDOI
Physiology of obesity and effects on lung function.
Cheryl M. Salome,Gregory G. King,Gregory G. King,Gregory G. King,Norbert Berend,Norbert Berend +5 more
TLDR
Obesity has effects on lung function that can reduce respiratory well-being, even in the absence of specific respiratory disease, and may also exaggerate the effects of existing airway disease.Abstract:
In obese people, the presence of adipose tissue around the rib cage and abdomen and in the visceral cavity loads the chest wall and reduces functional residual capacity (FRC). The reduction in FRC and in expiratory reserve volume is detectable, even at a modest increase in weight. However, obesity has little direct effect on airway caliber. Spirometric variables decrease in proportion to lung volumes, but are rarely below the normal range, even in the extremely obese, while reductions in expiratory flows and increases in airway resistance are largely normalized by adjusting for lung volumes. Nevertheless, the reduction in FRC has consequences for other aspects of lung function. A low FRC increases the risk of both expiratory flow limitation and airway closure. Marked reductions in expiratory reserve volume may lead to abnormalities in ventilation distribution, with closure of airways in the dependent zones of the lung and ventilation perfusion inequalities. Greater airway closure during tidal breathing is associated with lower arterial oxygen saturation in some subjects, even though lung CO-diffusing capacity is normal or increased in the obese. Bronchoconstriction has the potential to enhance the effects of obesity on airway closure and thus on ventilation distribution. Thus obesity has effects on lung function that can reduce respiratory well-being, even in the absence of specific respiratory disease, and may also exaggerate the effects of existing airway disease.read more
Citations
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Journal ArticleDOI
Ventilatory Response at Rest and During Maximal Exercise Testing in Patients with Severe Obesity Before and After Sleeve Gastrectomy.
Nicola Borasio,Daniel Neunhaeuserer,Andrea Gasperetti,Claudia Favero,Veronica Baioccato,Marco Bergamin,Luca Busetto,Mirto Foletto,Roberto Vettor,Andrea Ermolao +9 more
TL;DR: The weight loss induced by SG led to less burdensome restrictive limitations of the respiratory system and to a reduction of ventilation at rest and during exercise, possibly explained by an increased ventilatory efficiency and a decrease in oxygen demands.
Journal ArticleDOI
Motor control exercises of the lumbar-pelvic region improve respiratory function in obese men. A pilot study.
Emanuela Bezzoli,Dianne Andreotti,Lucia Pianta,Martina Mascheroni,Lorena Piccinno,Luca Puricelli,Veronica Cimolin,Alberto Salvadori,Franco Codecasa,Paolo Capodaglio +9 more
TL;DR: Preliminary evidence that breathing, postural control, and spinal stability are intertwined is provided that positive respiratory effects in obese men can be obtained by prescribing specific motor control exercises of the lumbar-pelvic muscles.
Journal ArticleDOI
Influence of Central Obesity Assessed by Conicity Index on Lung Age in Young Adults.
Usha Shenoy,Jagadamba +1 more
TL;DR: Lung age can be used as a potential psychological tool to show an individual with central obesity that there is premature aging of their lungs.
Journal ArticleDOI
Correlation of lung function and respiratory muscle strength with functional exercise capacity in obese individuals with obstructive sleep apnea syndrome.
Thays Maria da Conceição Silva Carvalho,Anísio Francisco Soares,Danielle Cristina Silva Clímaco,Isaac Vieira Secundo,Anna Myrna Jaguaribe de Lima +4 more
TL;DR: It was found that a decline in lung function, but not in respiratory muscle strength, was associated with exercise tolerance in these patients, and this sample of obese subjects with untreated OSAS was below normal.
Journal ArticleDOI
Pediatric Obesity-Related Asthma: The Role of Nutrition and Nutrients in Prevention and Treatment
Valeria Calcaterra,Valeria Calcaterra,Elvira Verduci,Elvira Verduci,Michele Ghezzi,Hellas Cena,Martina Chiara Pascuzzi,Corrado Regalbuto,Rossella Lamberti,Virginia Rossi,Matteo Manuelli,Alessandra Bosetti,Gian Vincenzo Zuccotti,Gian Vincenzo Zuccotti +13 more
TL;DR: In this paper, the authors presented and discussed more recent literature on asthma associated with obesity among children, focusing on the risk of asthma among children with obesity, asthma as a result of obesity focusing on role of adipose tissue as a mediator of systemic and local airway inflammation implicated in asthma regulation, and the impact of nutrition and nutrients in the development of asthma.
References
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Journal ArticleDOI
The Effects of Body Mass Index on Lung Volumes
TL;DR: It was showed that BMI has significant effects on all of the lung volumes, and the greatest effects were on FRC and ERV, which occurred at BMI values < 30 kg/m2, which will assist clinicians when interpreting PFT results in patients with normal airway function.
Journal ArticleDOI
Effects of obesity on respiratory function
TL;DR: It is concluded that obesity does not usually preclude use of usual predictors, and an abnormal pulmonary function test value should be considered as caused by intrinsic lung disease and not by obesity, except in those with extreme obesity.
Journal ArticleDOI
Compliance of the respiratory system and its components in health and obesity.
A. Naimark,Reuben M. Cherniack +1 more
TL;DR: The compliance of the total respiratory system and its components was studied in normal and obese spontaneously breathing unanesthetized subjects and found that the former are more compliant than the latter.
Journal ArticleDOI
The effects of body mass on lung volumes, respiratory mechanics, and gas exchange during general anesthesia
Paolo Pelosi,M. Croci,I Ravagnan,Stefano Tredici,Alessia Pedoto,Alfredo Lissoni,Luciano Gattinoni +6 more
TL;DR: The effects of body mass index (BMI) on functional residual capacity (FRC), respiratory mechanics, respiratory mechanics (compliance and resistance), gas exchange, and the inspiratory mechanical work done per liter of ventilation during general anesthesia are investigated.
Journal ArticleDOI
Effects of Obesity on Respiratory Resistance
TL;DR: It is suggested that in addition to the elastic load, obese subjects have to overcome increased respiratory resistance resulting from the reduction in lung volumes related to being overweight.
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