Journal ArticleDOI
Picobirnavirus infections: viral persistence and zoonotic potential
Balasubramanian Ganesh,Krisztián Bányai,Vito Martella,Ferenc Jakab,Gisela Masachessi,Nobumichi Kobayashi +5 more
TLDR
The public health aspects of PBV infection, especially its possible association with zoonosis is analyzed, as well as evidence has been found for genetic relatedness between human and animalPBV strains, suggesting extant crossing points in the ecology and evolution of heterologous PBV strains.Citations
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Kingdom-Agnostic Metagenomics and the Importance of Complete Characterization of Enteric Microbial Communities
TL;DR: It is shown that bacteria are not the only complex and important microbes in the human intestine, and studies of associations between the microbiome and intestinal pathology should incorporate kingdom-agnostic approaches if to fully understand intestinal health and disease.
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Nearly Constant Shedding of Diverse Enteric Viruses by Two Healthy Infants
TL;DR: It is demonstrated that frequent enteric infections with diverse viruses occur during early childhood in the absence of severe clinical symptoms.
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Pathogens transmitted in animal feces in low- and middle-income countries.
Miranda J Delahoy,Breanna K. Wodnik,Lydia McAliley,Gauthami Penakalapati,Jenna Swarthout,Matthew C. Freeman,Karen Levy +6 more
TL;DR: Five pathogens of highest concern cause approximately one million annual deaths in low-/middle-income countries and this review can help prioritize interventions and regions for animal feces control.
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Identification of Multiple Novel Viruses, Including a Parvovirus and a Hepevirus, in Feces of Red Foxes
Rogier Bodewes,Joke van der Giessen,Bart L. Haagmans,Albert D. M. E. Osterhaus,Saskia L. Smits +4 more
TL;DR: The fecal viral microbiome of 13 red foxes was evaluated by random PCR in combination with next-generation sequencing, and various novel viruses, including a parvovirus, bocavirus, adeno-associated virus, hepevirus, astroviruses, and picobirnaviruses were identified.
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A Preliminary Study of Viral Metagenomics of French Bat Species in Contact with Humans: Identification of New Mammalian Viruses
Laurent Dacheux,Minerva Cervantes-Gonzalez,Ghislaine Guigon,Jean-Michel Thiberge,Mathias Vandenbogaert,Corinne Maufrais,Valérie Caro,Hervé Bourhy +7 more
TL;DR: It is demonstrated that bats naturally harbor viruses from many different families, most of which infect mammals, and may constitute a major reservoir of viral diversity that should be analyzed carefully, to determine the role played by bats in the spread of zoonotic viral infections.
References
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MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
TL;DR: Version 4 of MEGA software expands on the existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automatic and manual sequence alignment, analyzing sequence alignments to estimate evolutionary distances, inferring phylogenetic trees, and testing evolutionary hypotheses.
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Rotavirus and Severe Childhood Diarrhea
TL;DR: Application of this proportion to the recent World Health Organization estimates of diarrhea-related childhood deaths gave an estimated 611,000 rotavirus-related deaths.
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Rapid diagnosis of rotavirus infection by direct detection of viral nucleic acid in silver-stained polyacrylamide gels.
TL;DR: A rapid simple technique based on the sensitive detection of rotavirus double-stranded RNA genome segments separated in polyacrylamide gels, which is comparable with that of electron microscopy or enzyme-linked immunosorbent assay.
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Cross-Species Virus Transmission and the Emergence of New Epidemic Diseases
Colin R. Parrish,Edward C. Holmes,David M. Morens,Eun Chung Park,Donald S. Burke,Charles H. Calisher,Catherine A. Laughlin,Linda J. Saif,Peter Daszak +8 more
TL;DR: What is known about host switching leading to viral emergence from known examples is reviewed, considering the evolutionary mechanisms, virus-host interactions, host range barriers to infection, and processes that allow efficient host-to-host transmission in the new host population.
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RNA Viral Community in Human Feces: Prevalence of Plant Pathogenic Viruses
Tao Zhang,Mya Breitbart,Wah Heng Lee,Jin-Quan Run,Chia-Lin Wei,Shirlena Wee Ling Soh,Martin L. Hibberd,Edison T. Liu,Forest Rohwer,Yijun Ruan +9 more
TL;DR: The most abundant fecal virus in this study was pepper mild mottle virus (PMMV), which was found in high concentrations—up to 109 virions per gram of dry weight fecal matter, indicating that this plant virus is prevalent in the human population.