Journal ArticleDOI
Preparation of copper-containing bioactive glass/eggshell membrane nanocomposites for improving angiogenesis, antibacterial activity and wound healing
Jinyan Li,Dong Zhai,Fang Lv,Qingqing Yu,Hongshi Ma,Jinbo Yin,Zhengfang Yi,Mingyao Liu,Jiang Chang,Chengtie Wu +9 more
TLDR
The results indicate that Cu(2+) ions released from Cu-BG/ESM nanocomposite films play an important role for improving both angiogenesis and antibacterial activity and the prepared nanocomPOSite films combined Cu-containing BG nanocoatings with ESM are a promising biomaterial for wound healing application.About:
This article is published in Acta Biomaterialia.The article was published on 2016-05-01. It has received 236 citations till now.read more
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity
TL;DR: It is demonstrated that it is possible to develop multifunctional scaffolds by combining enhanced angiogenesis potential, osteostimulation, and antibacterial properties for the treatment of large bone defects.
Journal ArticleDOI
Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing.
Mirza Ali Mofazzal Jahromi,Parham Sahandi Zangabad,Seyed Masoud Moosavi Basri,Keyvan Sahandi Zangabad,Ameneh Ghamarypour,Amir Reza Aref,Mahdi Karimi,Michael R. Hamblin,Michael R. Hamblin +8 more
TL;DR: The present review covers the physiology of skin, burn classification, burn wound pathogenesis, animal models of burn wound infection, and various topical therapeutic approaches designed to combat infection and stimulate healing, including biological based approaches and nanotechnology-based wound healing approaches as a revolutionizing area.
Journal ArticleDOI
Self-Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?
Sepehr Talebian,Mehdi Mehrali,Nayere Taebnia,Cristian Pablo Pennisi,Firoz Babu Kadumudi,Javad Foroughi,Masoud Hasany,Mehdi Nikkhah,Mohsen Akbari,Gorka Orive,Alireza Dolatshahi-Pirouz,Alireza Dolatshahi-Pirouz +11 more
TL;DR: The recent progress in the development of multifunctional and self‐healable hydrogels for various tissue engineering applications is discussed in detail and their potential applications within the rapidly expanding areas of bioelectronics, cyborganics, and soft robotics are highlighted.
Journal ArticleDOI
Anti-oxidant electroactive and antibacterial nanofibrous wound dressings based on poly(ε-caprolactone)/quaternized chitosan-graft-polyaniline for full-thickness skin wound healing
TL;DR: In this article, a series of antibacterial, anti-oxidant and electroactive nanofibrous membranes were fabricated by electrospinning poly(e-caprolactone) (PCL) and quaternized chitosan-graft-polyaniline (QCSP) polymer solutions which combined the good mechanical property of PCL and multi-functionality of QCSP.
References
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Journal ArticleDOI
Bioactive glass in tissue engineering
Mohamed N. Rahaman,Delbert E. Day,B. Sonny Bal,Qiang Fu,Steven B. Jung,Lynda F. Bonewald,Antoni P. Tomsia +6 more
TL;DR: Recent work has shown the ability of bioactive glass to promote angiogenesis, which is critical to numerous applications in tissue regeneration, such as neovascularization for bone regeneration and the healing of soft tissue wounds.
Journal ArticleDOI
Extracellular-matrix tethering regulates stem-cell fate
Britta Trappmann,Julien E. Gautrot,Julien E. Gautrot,John T. Connelly,John T. Connelly,Daniel G. T. Strange,Yuan Li,Michelle L. Oyen,Martien A. Cohen Stuart,Heike Boehm,Heike Boehm,Bojun Li,Viola Vogel,Joachim P. Spatz,Joachim P. Spatz,Fiona M. Watt,Wilhelm T. S. Huck,Wilhelm T. S. Huck +17 more
TL;DR: It is concluded that stem cells exert a mechanical force on collagen fibres and gauge the feedback to make cell-fate decisions, and are regulated by the elastic modulus of PAAm.
Journal ArticleDOI
Modulation of cell adhesion, proliferation and differentiation on materials designed for body implants.
TL;DR: The interaction of cells and tissues with artificial materials designed for applications in biotechnologies and in medicine is governed by the physical and chemical properties of the material surface, including surface roughness and surface topography.
Journal ArticleDOI
A review of tissue-engineered skin bioconstructs available for skin reconstruction
TL;DR: Those materials already commercially available for clinical use as well as to give a short insight to those under development are described to provide skin scientists/tissue engineers with the information required to move closer to achieving the ultimate goal of an off-the-shelf, complete full-thickness skin replacement.
Journal ArticleDOI
Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity
TL;DR: In this paper, a copper-containing mesoporous bioactive glass (Cu-MBG) scaffolds with interconnective large pores (several hundred micrometer) and well-ordered mesopore channels (around 5 nm) were used to develop multifunctional bioactive scaffolds, which combine angiogenesis capacity, osteostimulation, and antibacterial properties for regenerating lost bone tissues.