Journal ArticleDOI
Prevalence and characterization of methicillin-resistant Staphylococcus pseudintermedius from symptomatic companion animals in Northern Italy: Clonal diversity and novel sequence types.
Maria Luisa Menandro,Giorgia Dotto,Alessandra Mondin,Marco Martini,L. Ceglie,Daniela Pasotto +5 more
TLDR
A high prevalence of MRSP amongst clinical samples from pets in Italy is confirmed and these isolates show multidrug resistance features that are of concern both in veterinary and human medicine for clinical and epidemiological reasons.Abstract:
The aim of this study was to assess the prevalence, the genotypic diversity, the antimicrobial resistance traits of canine and feline clinical methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates in a diagnostic laboratory in Italy during 2015-2016. All isolates were characterized by multilocus sequence typing (MLST), staphylococcal cassette chromosome (SCC)- mec typing and staphylococcal protein A ( spa )-typing. The resistance profiles were assessed by antimicrobial susceptibility testing and confirmed genotypically by the detection of mecA gene and by microarray analyses. The prevalence of MRSP isolates was high (31.6%). All the strains were multidrug resistant and the most frequent clone was ST71-SCC mec type II-III. These results confirm a high prevalence of MRSP amongst clinical samples from pets in Italy. These isolates show multidrug resistance features that are of concern both in veterinary and human medicine for clinical and epidemiological reasons.read more
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Clonal diversity and antimicrobial resistance of methicillin-resistant staphylococcus pseudintermedius isolated from canine pyoderma
Vanessa Silva,Ana Oliveira,Vera Manageiro,Manuela Caniça,Diogo Contente,Rosa Capita,Carlos Alonso-Calleja,Isabel Carvalho,José Luis Capelo,Gilberto Igrejas,Patrícia Poeta +10 more
TL;DR: The emergence of methicillin-resistant Staphylococcus pseudintermedius (MRSP) antimicrobial resistance and epidemic genetic lineages is posing a challenge in veterinary medicine due to the limited therapeutical options as mentioned in this paper.
Journal ArticleDOI
Patterns of antimicrobial, multidrug and methicillin resistance among Staphylococcus spp. isolated from canine specimens submitted to a diagnostic laboratory in Tennessee, USA: a descriptive study
TL;DR: In this article , the authors investigated patterns of antimicrobial, multidrug, and methicillin resistance among four Staphylococcus spp. commonly isolated from canine clinical specimens submitted to the Clinical Bacteriology Laboratory at the University of Tennessee College of Veterinary Medicine (UTCVM).
Journal ArticleDOI
On Gram-Positive- and Gram-Negative-Bacteria-Associated Canine and Feline Skin Infections: A 4-Year Retrospective Study of the University Veterinary Microbiology Diagnostic Laboratory of Naples, Italy
TL;DR: A 4-year retrospective study (2016-2019) of selected routine bacteriological examinations of the veterinary microbiology laboratory of the University Veterinary Teaching Hospital of Naples (Italy) was carried out.
Journal ArticleDOI
Clindamycin resistance of skin derived Staphylococcus pseudintermedius is higher in dogs with a history of antimicrobial therapy.
TL;DR: It is recommended that bacterial culture and susceptibility testing be pursued before prescribing systemic antimicrobials, and clindamycin should be regarded as the preferred treatment option if susceptibility is confirmed, due to its narrow spectrum and reduced selective pressure for MRSP.
Journal ArticleDOI
Severe Pneumonia Caused by Methicillin-Resistant <i>Staphylococcus pseudintermedius</i> in an Oncology Patient: Case Report and Literature Review
TL;DR: The first case of methicillin-resistant Staphylococcus pseudintermedius was reported in a 12-year-old immunocompromised child with refractory anaplastic ependymoma, presenting with life-threatening pneumonia and bacteremia as discussed by the authors .
References
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Book
Performance standards for antimicrobial susceptibility testing
Melvin P. Weinstein,Clinical +1 more
TL;DR: The tabular information presented here represents the most current information for drug selection, interpretation, and QC using the procedures standardized in the most recent editions of M02, M07, and M11, and users should replace outdated editions with the current editions of CLSI documents.
Journal ArticleDOI
Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions.
Yoko Kondo,Teruyo Ito,Xiao Xue Ma,Shinya Watanabe,Barry N. Kreiswirth,Jerome Etienne,Keiichi Hiramatsu +6 more
TL;DR: The SCCmec type assignments were identical to those made with a PCR system that uses numerous primer pairs to identify genes or gene alleles, and the system of six M-PCRs is thus a convenient and reliable method for typing S CCmec elements.
Journal ArticleDOI
Methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in veterinary medicine.
TL;DR: The relative importance of these staphylococci on different animal species varies, as do the concerns about zoonotic transmission, yet it is clear that both present a challenge to veterinary medicine.
Journal ArticleDOI
Clonal spread of methicillin-resistant Staphylococcus pseudintermedius in Europe and North America: an international multicentre study
Vincent Perreten,Kristina Kadlec,Stefan Schwarz,Ulrika Grönlund Andersson,Maria Finn,Christina Greko,Arshnee Moodley,Stephen A. Kania,Linda A. Frank,David A. Bemis,Alessia Franco,Manuela Iurescia,Antonio Battisti,Birgitta Duim,Jaap A. Wagenaar,Engeline van Duijkeren,J. Scott Weese,J. Ross Fitzgerald,Alexandra Rossano,Luca Guardabassi +19 more
TL;DR: Two major clonal MRSP lineages have disseminated in Europe and North America and regardless of their geographical or clonal origin, the isolates displayed resistance to the major classes of antibiotics used in veterinary medicine and thus infections caused by MRSP isolates represent a serious therapeutic challenge.
Journal ArticleDOI
Review on methicillin-resistant Staphylococcus pseudintermedius
Engeline van Duijkeren,Boudewijn Catry,Christina Greko,Miguel A. Moreno,M. Constança Matias Ferreira Pomba,Satu Pyörälä,Modestas Ružauskas,Pascal Sanders,E. John Threlfall,Jordi Torren-Edo,Karolina Törneke +10 more
TL;DR: Research on MRSP is reviewed with a focus on occurrence, methods used for identification, risk factors for colonization and infection, zoonotic potential and control options, and potential areas for future research are discussed.