Journal ArticleDOI
Principles of chemotherapy.
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TLDR
The basic principles for the safe and effective use of various chemotherapeutic agents in the treatment of neoplastic diseases are reviewed.About:
This article is published in Clinical Techniques in Small Animal Practice.The article was published on 2003-05-01. It has received 107 citations till now.read more
Citations
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Nanomaterials for theranostics: recent advances and future challenges.
Eun Kyung Lim,Eun Kyung Lim,Taekhoon Kim,Taekhoon Kim,Soonmyung Paik,Seungjoo Haam,Yong Min Huh,Kwangyeol Lee +7 more
TL;DR: Challenges Eun-Kyung Lim,†,‡,§ Taekhoon Kim, Soonmyung Paik, Seungjoo Haam, Yong-Min Huh,*,† and Kwangyeol Lee
Journal ArticleDOI
Targeting Mammalian Target of Rapamycin Synergistically Enhances Chemotherapy-Induced Cytotoxicity in Breast Cancer Cells
Wallace H. Mondesire,Weiguo Jian,Haixia Zhang,Joe Ensor,Mien Chie Hung,Gordon B. Mills,Funda Meric-Bernstam +6 more
TL;DR: Rapamycin potentiates the cytotoxicity of selected chemotherapeutic agents in cell lines sensitive to the effects of rapamycin due to aberrations in the phosphatidylinositol 3′-kinase/Akt pathway, suggesting that combination therapy may be effective in patients selected for aberration in this pathway.
Journal ArticleDOI
A pH-responsive mesoporous silica nanoparticles-based multi-drug delivery system for overcoming multi-drug resistance
TL;DR: The MDR-overcoming mechanism was proved to be a synergistic cell cycle arrest/apoptosis-inducing effect resulted from the chemosensitization of the surfactant CTAB.
Journal ArticleDOI
Assessing biocompatibility of graphene oxide-based nanocarriers: A review
TL;DR: An overview on the effect of GO properties on interactions with cells such as red blood cells, macrophages and cell lines, and experimental organisms including rodents, rabbits and Zebrafish is provided, offering some guidelines for development of safe GO-based nanocarriers.
Journal ArticleDOI
Advanced Functional Nanomaterials for Theranostics
Haoyuan Huang,Jonathan F. Lovell +1 more
TL;DR: Some general design considerations of advanced theranostic materials and challenges of their use, from both diagnostic and therapeutic perspectives, are discussed.
References
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Book
Cancer : Principles and Practice of Oncology
TL;DR: Part I: Molecular Biology of Cancer Molecular Methods in Oncology Section 1. Amplification Techniques Section 2. RNA Interference Section 3. cDNA arrays Section 4. Tissue arrays Section 5. Cytogenetics Section 6. Bioinformatics Genomics and Proteomics Molecular Targets in oncology.
Book
Small Animal Clinical Oncology
TL;DR: The Pathology of Neoplasia, including Tumor Biology, Immunology and Biologic Therapy of Cancer, and New Developments in Cancer Therapy are presented.
Journal ArticleDOI
Adjuvant methotrexate and citrovorum-factor treatment of osteogenic sarcoma.
TL;DR: It is indicated that systemic (adjuvant) chemotherapy delays relapse and may provide defiency to patients with osteogenic sarcoma with follow-up periods of two to 23 months.
Journal ArticleDOI
Amputation and Carboplatin for Treatment of Dogs With Osteosarcoma: 48 Cases (1991 to 1993)
Philip J. Bergman,E. Gregory MacEwen,Ilene D. Kurzman,Carolyn J. Henry,A S Hammer,Deborah W. Knapp,Ann Hale,Stephen A. Kruth,Mary K. Klein,Jeffrey S. Klausner,Alan M. Norris,Dudley L. McCaw,Rodney C. Straw,Stephen J. Withrow +13 more
TL;DR: Carboplatin appears to be a well-tolerated chemotherapeutic drug that can be given safely every 21 days at a dose of 300 mg/m2 and Neutropenia was the dose-limiting toxicity in this study.
Journal ArticleDOI
Evaluation of prognostic factors and sequential combination chemotherapy with doxorubicin for canine lymphoma.
TL;DR: Fifty-five dogs with lymphoma were treated using a doxorubicin-based sequential combination chemotherapy protocol and prognostic factors identified sex, World Health Organization substage, and serum calcium as statistically significant variables for both survival and remission duration.