Journal ArticleDOI
A pH-responsive mesoporous silica nanoparticles-based multi-drug delivery system for overcoming multi-drug resistance
TLDR
The MDR-overcoming mechanism was proved to be a synergistic cell cycle arrest/apoptosis-inducing effect resulted from the chemosensitization of the surfactant CTAB.About:
This article is published in Biomaterials.The article was published on 2011-10-01. It has received 338 citations till now. The article focuses on the topics: Drug delivery & Mesoporous silica.read more
Citations
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Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
TL;DR: The in vitro and in vivo biocompatibility and biotranslocation of MSNs are discussed in relation to their chemophysical properties including particle size, surface properties, shape, and structure.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Clinical development and potential of photothermal and photodynamic therapies for cancer
TL;DR: An overview of the current clinical progress of phototherapies for cancer and discuss the emerging preclinical bioengineering approaches that have the potential to overcome challenges in this area and thus improve the efficiency and utility of such treatments are provided.
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Overcoming the Achilles' heel of photodynamic therapy.
TL;DR: It is highly expected that deep PDT will be developed as a versatile, depth/oxygen-independent and minimally invasive strategy for treating a variety of malignant tumours at deep locations.
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Nanoparticles as drug delivery systems
TL;DR: Various nanostructures, including liposomes, polymers, dendrimers, silicon or carbon materials, and magnetic nanoparticles, have been tested as carriers in drug delivery systems and their connections with drugs are analyzed.
References
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Journal ArticleDOI
Emerging applications of stimuli-responsive polymer materials
Martien A. Cohen Stuart,Wilhelm T. S. Huck,Jan Genzer,Marcus Müller,Christopher K. Ober,Manfred Stamm,Gleb B. Sukhorukov,Igal Szleifer,Vladimir V. Tsukruk,Marek W. Urban,Françoise M. Winnik,Stefan Zauscher,Igor Luzinov,Sergiy Minko +13 more
TL;DR: This work reviews recent advances and challenges in the developments towards applications of stimuli-responsive polymeric materials that are self-assembled from nanostructured building blocks and provides a critical outline of emerging developments.
Journal ArticleDOI
Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging
Patricia Horcajada,Tamim Chalati,Christian Serre,Brigitte Gillet,Catherine Sebrié,Tarek Baati,Jarrod F. Eubank,Daniela Heurtaux,Pascal Clayette,Christine Kreuz,Jong-San Chang,Young Kyu Hwang,Véronique Marsaud,Phuong-Nhi Bories,Luc Cynober,Sophie Gil,Gérard Férey,Patrick Couvreur,Ruxandra Gref +18 more
TL;DR: It is shown that specific non-toxic porous iron(III)-based metal-organic frameworks with engineered cores and surfaces, as well as imaging properties, function as superior nanocarriers for efficient controlled delivery of challenging antitumoural and retroviral drugs against cancer and AIDS.
Journal ArticleDOI
Global Patterns of Cancer Incidence and Mortality Rates and Trends
TL;DR: Changing global incidence and mortality patterns for select common cancers and the opportunities for cancer prevention in developing countries are described.
Journal ArticleDOI
Generalized synthesis of periodic surfactant/inorganic composite materials
Qisheng Huo,David I. Margolese,Ulrike Ciesla,Pingyun Feng,Thurman E. Gier,Peter Sieger,R. Leon,Pierre Petroff,Ferdi Schüth,Ferdi Schüth,Galen D. Stucky +10 more
TL;DR: In this article, a generalized approach to the synthesis of periodic mesophases of metal oxides and cationic or anionic surfactants under a range of pH conditions is presented.