Journal ArticleDOI
Radiation-induced cataracts: the Health Protection Agency’s response to the ICRP statement on tissue reactions and recommendation on the dose limit for the eye lens
TLDR
Although further work is desirable to quantify better the risk at low doses and following protracted exposures, along with research into the mechanistic basis for radiation cataractogenesis to inform selection of risk projection models, the HPA endorses the conclusion reached by the ICRP in their 2011 statement that the equivalent dose limit should be reduced from 150 to 20 mSv per year.Abstract:
This paper presents the response of the Health Protection Agency (HPA) to the 2011 statement from the International Commission on Radiological Protection (ICRP) on tissue reactions and recommendation of a reduced dose limit for the lens of the eye. The response takes the form of a brief review of the most recent epidemiological and mechanistic evidence. This is presented together with a discussion of dose limits in the context of the related risk and the current status of eye dosimetry, which is relevant for implementation of the limits. It is concluded that although further work is desirable to quantify better the risk at low doses and following protracted exposures, along with research into the mechanistic basis for radiation cataractogenesis to inform selection of risk projection models, the HPA endorses the conclusion reached by the ICRP in their 2011 statement that the equivalent dose limit for the lens of the eye should be reduced from 150 to 20 mSv per year, averaged over a five year period, with no year's dose exceeding 50 mSv.read more
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Journal ArticleDOI
Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research.
Elizabeth A. Ainsbury,Stephen Barnard,Scott Bright,Claudia Dalke,Miguel Jarrin,Sarah Kunze,Richard Tanner,Joseph R. Dynlacht,Roy A. Quinlan,Jochen Graw,Munira Kadhim,Nobuyuki Hamada +11 more
TL;DR: A fuller understanding of how exposure to relatively low doses of IR promotes induction and/or progression of IR-induced cataracts will have important implications for prevention and treatment of this disease, as well as for the field of radiation protection.
Journal ArticleDOI
2018 ACC/HRS/NASCI/SCAI/SCCT Expert Consensus Document on Optimal Use of Ionizing Radiation in Cardiovascular Imaging: Best Practices for Safety and Effectiveness: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways.
John W. Hirshfeld,Victor A. Ferrari,Frank M. Bengel,Lisa Bergersen,Charles E. Chambers,Andrew J. Einstein,Mark J. Eisenberg,Mark A. Fogel,Thomas C. Gerber,David E. Haines,Warren K. Laskey,Marian C. Limacher,Kenneth J. Nichols,Daniel A. Pryma,Gilbert L. Raff,Geoffrey D. Rubin,Donnette Smith,Arthur E. Stillman,Suma A. Thomas,Thomas T. Tsai,Louis K. Wagner,L. Samuel Wann +21 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which marijuana was legal in America.
Journal ArticleDOI
Eye lens monitoring for interventional radiology personnel: dosemeters, calibration and practical aspects of H-p(3) monitoring. A 2015 review
Eleftheria Carinou,Paolo Ferrari,Olivera Ciraj Bjelac,Merce Gingaume,Marta Sans Merce,Una O’Connor +5 more
TL;DR: The paper concludes that the use of a dosemeter placed at collar level outside the lead apron can provide a useful first estimate of the eye lens exposure, however, for workplaces with estimated annual equivalent dose to the eye Lens close to the dose limit, specific eye lens monitoring should be performed.
Journal ArticleDOI
Low dose or low dose rate ionizing radiation-induced health effect in the human.
Feng Ru Tang,K. Loganovsky +1 more
TL;DR: Empirical and clinical studies show that LDIR or LDRIR exposure may induce cancer, congenital abnormalities, cardiovascular and cerebrovascular diseases, cognitive and other neuropsychiatric disorders, cataracts and other eye and somatic pathology (endocrine, bronchopulmonary, digestive, etc).
Journal ArticleDOI
Assessment of eye and body dose for interventional radiologists, cardiologists, and other interventional staff
Colin J. Martin,J S Magee +1 more
TL;DR: An alternative approach to personnel dose monitoring in radiology applications using a collar dosimeter worn outside the lead apron as the first dosimeter is proposed, which might be used in prior risk assessments to establish monitoring practice.
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Age-related nuclear cataract-oxidation is the key.
TL;DR: In this paper, it was shown that the concentration of nuclear glutathione (GSH) in the center of the lens can be maintained above 2 mm, provided that GSH levels can not be decreased by reactive small molecules.