Report from the American Society of Transplantation on frailty in solid organ transplantation
Jon A. Kobashigawa,Darshana Dadhania,Sangeeta Bhorade,Deborah Adey,Joseph R. Berger,Geetha Bhat,Marie Budev,Andres Duarte-Rojo,Michael A. Dunn,Shelley A. Hall,Meera N. Harhay,Kirsten L. Johansen,Susan M. Joseph,Cassie C. Kennedy,Evan P. Kransdorf,Krista L. Lentine,Raymond J. Lynch,Mara McAdams-DeMarco,Shunji Nagai,Michael Olymbios,Jignesh Patel,Sean Pinney,Joanna Schaenman,Dorry L. Segev,Palak Shah,Lianne G. Singer,Jonathan P. Singer,Christopher J. Sonnenday,Puneeta Tandon,Elliot B. Tapper,Stefan G. Tullius,Michael E. Wilson,Martin R. Zamora,Jennifer C. Lai +33 more
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TLDR
This conference achieved its intent to highlight the importance of frailty in organ transplantation and to plant the seeds for further discussion and research in this field.About:
This article is published in American Journal of Transplantation.The article was published on 2018-12-22 and is currently open access. It has received 146 citations till now. The article focuses on the topics: Transplantation & Organ transplantation.read more
Citations
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Journal ArticleDOI
Frailty and Access to Kidney Transplantation
Christine E. Haugen,Nadia M. Chu,Hao Ying,Fatima Warsame,Courtenay M. Holscher,Niraj M. Desai,Miranda R. Jones,Silas P. Norman,Daniel C. Brennan,Jacqueline Garonzik-Wang,Jeremy D. Walston,Adam W. Bingaman,Dorry L. Segev,Mara McAdams-DeMarco +13 more
TL;DR: Frailty is associated with lower chance of listing and lower rate of transplant, and is a potentially modifiable risk factor, in patients with ESKD.
Journal ArticleDOI
An overview of frailty in kidney transplantation: Measurement, management and future considerations
Meera N. Harhay,Maya K. Rao,Kenneth J. Woodside,Kirsten L. Johansen,Krista L. Lentine,Stefan G. Tullius,Ronald F. Parsons,Tarek Alhamad,Joseph R. Berger,Xingxing S. Cheng,Jaqueline Lappin,Raymond J. Lynch,Sandesh Parajuli,Jane C. Tan,Dorry L. Segev,Dorry L. Segev,Bruce Kaplan,Jon A. Kobashigawa,Darshana Dadhania,Mara McAdams-DeMarco,Mara McAdams-DeMarco +20 more
TL;DR: A review of studies in which frailty has been applied to pre- and post-kidney transplantation (KT) populations underscores the need for a disease-specific frailty metric that can be used to monitor KT candidates and recipients.
Journal ArticleDOI
Use of Ventricular Assist Devices and Heart Transplantation for Advanced Heart Failure.
TL;DR: The significant improvement in outcomes now possible with durable ventricular assist devices has led to a significant increase in their use, which now exceeds the volume of heart transplants in the United States, with the greatest growth in use for those not considered to be candidates for heart transplantation.
Journal ArticleDOI
ESPEN guideline on clinical nutrition in hospitalized patients with acute or chronic kidney disease.
Enrico Fiaccadori,Alice Sabatino,Rocco Barazzoni,Juan Jesus Carrero,Adamasco Cupisti,Elisabeth De Waele,Joop Jonckheer,Pierre Singer,Cristina Cuerda +8 more
TL;DR: In this paper, the authors provide evidence-based recommendations for clinical nutrition in hospitalized patients with acute kidney disease (AKD) and chronic kidney disease(CKD) using a structured consensus process, in order to update the ESPEN Guidelines on Enteral (2006) and Parenteral (2009) Nutrition in Adult Renal Failure.
Journal ArticleDOI
Multicenter study to transplant hepatitis C-infected kidneys (mythic): An open-label study of combined glecaprevir and pibrentasvir to treat recipients of transplanted kidneys from deceased donors with hepatitis c virus infection
Meghan E. Sise,David S. Goldberg,Jens Kort,Douglas E. Schaubel,Rita R. Alloway,Christine M. Durand,Robert J. Fontana,Robert S. Brown,John J. Friedewald,Stacey Prenner,J. Richard Landis,Melissa Fernando,Caitlin Phillips,E. Steve Woodle,Adele Rike-Shields,Kenneth E. Sherman,Nahel Elias,Winfred W. Williams,Jenna L. Gustafson,Niraj M. Desai,Brittany Barnaba,Silas P. Norman,Mona D. Doshi,Samuel Sultan,Meredith J. Aull,Josh Levitsky,Dianne S. Belshe,Raymond T. Chung,Peter P. Reese +28 more
TL;DR: A prospective trial to transplant 30 kidneys from deceased donors with HCV viremia into HCV-uninfected recipients, followed by 8 weeks of once-daily coformulated glecaprevir and pibrentasvir, demonstrated safety and efficacy.
References
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Frailty in Older Adults Evidence for a Phenotype
Linda P. Fried,Catherine M. Tangen,Jeremy D. Walston,Anne B. Newman,Calvin H. Hirsch,John S. Gottdiener,Teresa E. Seeman,Russell P. Tracy,Willem J. Kop,B Gregory Burke,Mary Ann McBurnie +10 more
TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
Journal Article
Cardiovascular Health Study Collaborative Research Group : Frailty in older adults : evidence for a phenotype
Journal ArticleDOI
Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People
Alfonso J. Cruz-Jentoft,Jean-Pierre Baeyens,Jürgen M. Bauer,Yves Boirie,Tommy Cederholm,Francesco Landi,Finbarr C. Martin,Jean-Pierre Michel,Yves Rolland,Stéphane M. Schneider,Eva Topinkova,Maurits Vandewoude,Mauro Zamboni +12 more
TL;DR: The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia as discussed by the authors.
Journal ArticleDOI
Frailty in elderly people
TL;DR: Developing more efficient methods to detect frailty and measure its severity in routine clinical practice would greatly inform the appropriate selection of elderly people for invasive procedures or drug treatments and would be the basis for a shift in the care of frail elderly people towards more appropriate goal-directed care.
Journal ArticleDOI
Frailty in Relation to the Accumulation of Deficits
TL;DR: Although based on a simple count, the frailty index shows several interesting properties, including a characteristic rate of accumulation, a submaximal limit, and characteristic changes with age in its distribution.
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