Journal ArticleDOI
Reproductive toxic potential of phthalate compounds - State of art review.
Sapna Sedha,Hoomin Lee,Siddhartha Singh,Sunil Kumar,Subodh Kumar Jain,Ajaz Ahmad,Yousef A. Bin Jardan,Sonam Sonwal,Shruti Shukla,Jesus Simal-Gandara,Jianbo Xiao,Yun Suk Huh,Young-Kyu Han,Vivek K. Bajpai +13 more
TLDR
In this paper, a review of the available literature on phthalates with respect to their reproductive toxic potential is presented, where common reproductive effects such as declined fertility, reduced testis weight, variations in accessory sex organs and several female reproductive disorders appeared to be largely associated with the transitional phthalate.About:
This article is published in Pharmacological Research.The article was published on 2021-03-04. It has received 44 citations till now. The article focuses on the topics: Phthalate & Benzyl butyl phthalate.read more
Citations
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Journal ArticleDOI
One Health challenges for pig reproduction.
TL;DR: The current state of the world challenges pig reproduction as an important part of One Health, which involves interrelationships between animal, human and environmental health as mentioned in this paper , and therefore more resilient pigs that can tolerate harsh environment but maintain high reproductive performance are needed.
Journal ArticleDOI
The mechanism of monobutyl phthalate -induced ferroptosis via TNF/IL6/STAT3 signal pathway in TM-3 cells.
TL;DR: In this article , the authors evaluated the mechanism of MBP-induced ferroptosis in reproductive damage, bioinformation analysis and experimental validation were used to evaluate the mechanism and the specific mechanism of reproductive injury caused by MBP.
Book ChapterDOI
Phthalates
TL;DR: In this paper , uses, metabolism, toxicology, pharmacology, and pathways of exposure to phthalates are reviewed, as well as their potential effects on the endocrine system.
Journal ArticleDOI
Synthesis of biodegradable material from banana peel
TL;DR: In this article , the effect of concentration of the plasticizer and binder on the biodegradability of bioplastic from banana peels was studied and the results showed that high amounts of glycerin and higher amounts of HCl were more effective in degradability.
Journal ArticleDOI
A Case–Control Study on the Effects of Plasticizers Exposure on Male Fertility
Lidia Caporossi,Paola Viganò,Enrico Paci,Silvia Capanna,Alessandra Alteri,Daniela Pigini,Giovanna Tranfo,Bruno Papaleo +7 more
TL;DR: In this paper , the urinary levels of seven phthalates and BPA were analyzed through HPLC/MS/MS and sperm parameters (volume, sperm concentration, total count of spermatozoa, and sperm motility).
References
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Journal ArticleDOI
Decrease in anogenital distance among male infants with prenatal phthalate exposure
Shanna H. Swan,Katharina M. Main,Fan Liu,Sara Stewart,Robin L. Kruse,Antonia M. Calafat,Catherine S. Mao,J. Bruce Redmon,Christine L. Ternand,S.J. Sullivan,J.Lynn Teague +10 more
TL;DR: The hypothesis that prenatal phthalate exposure at environmental levels can adversely affect male reproductive development in humans is supported.
Journal ArticleDOI
Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat.
L. Earl Gray,Joseph S. Ostby,Johnathan Furr,Matthew Price,D.N. Rao Veeramachaneni,Louise G. Parks +5 more
TL;DR: It is hypothesized that the phthalate esters that altered testis function in the pubertal male rat would also alter testisfunction in the fetal male and produce malformations of androgen-dependent tissues and, in summary, DEHP, BBP, and DINP all altered sexual differentiation, whereas DOTP, DEP, or DMP were ineffective at this dose.
Journal ArticleDOI
Human exposure to phthalates via consumer products
TL;DR: Oven baking of polymer clays may cause short-term, high-level inhalation exposures to higher molecular weight phthalates and cosmetics, personal care products, pharmaceuticals, nutritional supplements, herbal remedies and insecticides, may result in significant but poorly quantified human exposures.
Journal ArticleDOI
The estrogenic activity of phthalate esters in vitro.
TL;DR: A large number of phthalate esters were screened for estrogenic activity using a recombinant yeast screen and a selection of these was also tested for mitogenic effect on estrogen-responsive human breast cancer cells.
Journal ArticleDOI
The Plasticizer Diethylhexyl Phthalate Induces Malformations by Decreasing Fetal Testosterone Synthesis during Sexual Differentiation in the Male Rat
Louise G. Parks,Joe Ostby,Christy R. Lambright,Barbara D. Abbott,Gary R. Klinefelter,Norman J. Barlow,L. Earl Gray +6 more
TL;DR: Data indicate that DEHP disrupts male rat sexual differentiation by reducing T to female levels in the fetal male rat during a critical stage of reproductive tract differentiation.