Review of biosensing with whispering-gallery mode lasers
Nikita A. Toropov,Gema Cabello,Mariana Paula Serrano,Rithvik R. Gutha,Matías Rafti,Frank Vollmer +5 more
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TLDR
The most recent advances in biosensing with whisperinggallery modes (WGMs) are described in this paper, where the basic concepts of WGM resonators, the integration of gain media into various active WGM sensors and devices, and the cutting-edge advances in photonic devices for micro-and nanoprobing of biological samples that can be integrated with WGM lasers.Abstract:
Lasers are the pillars of modern optics and sensing. Microlasers based on whispering-gallery modes (WGMs) are miniature in size and have excellent lasing characteristics suitable for biosensing. WGM lasers have been used for label-free detection of single virus particles, detection of molecular electrostatic changes at biointerfaces, and barcode-type live-cell tagging and tracking. The most recent advances in biosensing with WGM microlasers are described in this review. We cover the basic concepts of WGM resonators, the integration of gain media into various active WGM sensors and devices, and the cutting-edge advances in photonic devices for micro- and nanoprobing of biological samples that can be integrated with WGM lasers.read more
Citations
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References
More filters
Journal ArticleDOI
Stimulated Optical Radiation in Ruby
TL;DR: Schawlow and Townes as discussed by the authors proposed a technique for the generation of very monochromatic radiation in the infra-red optical region of the spectrum using an alkali vapour as the active medium.
Journal ArticleDOI
Quantum dots versus organic dyes as fluorescent labels
TL;DR: This work compares and evaluates the differences in physicochemical properties of common fluorescent labels, focusing on traditional organic dyes and QDs, to provide a better understanding of the advantages and limitations of both classes of chromophores.
Journal ArticleDOI
The Quantum Theory of Optical Coherence
TL;DR: In this paper, a succession of correlation functions for the complex field strengths is defined, and a fully coherent field is defined as one whose correlation functions satisfy an infinite succession of stated conditions.
Journal ArticleDOI
Zero-Mode Waveguides for Single-Molecule Analysis at High Concentrations
Michael J. Levene,Jonas Korlach,Stephen Turner,Mathieu Foquet,Harold G. Craighead,Watt W. Webb +5 more
TL;DR: It is shown that arrays of zero-mode waveguides consisting of subwavelength holes in a metal film provide a simple and highly parallel means for studying single-molecule dynamics at micromolar concentrations with microsecond temporal resolution.
Journal ArticleDOI
Multiphoton microscopy in life sciences
TL;DR: Owing to the high NIR penetration depth, non‐invasive optical biopsies can be obtained from patients and ex vivo tissue by morphological and functional fluorescence imaging of endogenous fluorophores such as NAD(P)H, flavin, lipofuscin, porphyrins, collagen and elastin.
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