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Journal ArticleDOI

Risk Factors for Progression of Low-Grade Dysplasia in Patients With Barrett's Esophagus

TLDR
Overall, patients with BE and LGD have a low annual incidence of EAC, similar to nondysplastic BE, and there is significant interobserver variation in diagnosis, even among expert pathologists.
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This article is published in Gastroenterology.The article was published on 2011-10-01. It has received 243 citations till now.

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Iconographies supplémentaires de l'article : Low-grade dysplasia diagnosis ratio and progression metrics identify variable Barrett’s esophagus risk stratification proficiency in independent pathology practices

TL;DR: In this paper, the authors compare independent pathology practices using objective measures of BE risk stratification proficiency, including frequency of diagnosis and rate of progression, with high grade dysplasia (HGD) or adenocarcinoma (EAC) after the first diagnosis of LGD.
Journal ArticleDOI

Pathogenese und Prävention von ösophagealen Adenokarzinomen

TL;DR: Results show that stem cells from the stomach’s cardia are activated by alteration of the inflammatory microenvironment in the esophagus, which is presumably influenced by multiple factors such as age, gender, and obesity etc., alongside genetic and molecular changes.
Journal ArticleDOI

Measuring Quality in Barrett's Esophagus: Time to Embrace Quality Indicators.

TL;DR: In this paper, the authors align consensus statements based on the best available evidence and expert opinion from the United States and United Kingdom to develop robust and measurable quality indicators that help to ensure patients with Barrett's esophagus related neoplasia receive the highest possible quality of care uniformly.
References
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Journal ArticleDOI

Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus.

TL;DR: The guidelines for the diagnosis, surveillance and therapy of Barrett’s esophagus were originally published by the American College of Gastroenterology in 1998 and updated in 2002 and once again reviewed using the National Library of Medicine database.
Journal ArticleDOI

The Vienna classification of gastrointestinal epithelial neoplasia

TL;DR: The differences between Western and Japanese pathologists in the diagnostic classification of gastrointestinal epithelial neoplastic lesions can be resolved largely by adopting the proposed terminology, which is based on cytological and architectural severity and invasion status.
Journal ArticleDOI

Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications

TL;DR: A classification system for the epithelial changes that occur in ulcerative colitis was developed, which should be applicable to other forms of inflammatory bowel disease as well and makes use of standardized terminology, addresses specific problem areas, and offers practical solutions.
Journal ArticleDOI

The Role of Overdiagnosis and Reclassification in the Marked Increase of Esophageal Adenocarcinoma Incidence

TL;DR: The rising incidence of esophageal adenocarcinoma represents a real increase in disease burden and overdiagnosis can be excluded as an explanation for the rise in incidence.
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