Journal ArticleDOI
Risk Factors for Progression of Low-Grade Dysplasia in Patients With Barrett's Esophagus
Sachin Wani,Gary W. Falk,Jane Post,Lisa Yerian,Matthew Hall,Amy Wang,Neil Gupta,Srinivas Gaddam,Mandeep Singh,Vikas Singh,Keng-Yu Chuang,Vikram Boolchand,Hemanth Gavini,John Kuczynski,Priti Sud,Ajay Bansal,Amit Rastogi,Sharad C. Mathur,Patrick E. Young,Brooks D. Cash,John R. Goldblum,David A. Lieberman,Richard E. Sampliner,Prateek Sharma +23 more
TLDR
Overall, patients with BE and LGD have a low annual incidence of EAC, similar to nondysplastic BE, and there is significant interobserver variation in diagnosis, even among expert pathologists.About:
This article is published in Gastroenterology.The article was published on 2011-10-01. It has received 243 citations till now.read more
Citations
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Journal ArticleDOI
British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus
Rebecca C. Fitzgerald,Massimiliano di Pietro,Krish Ragunath,Yeng Ang,Jin-Yong Kang,Peter H. Watson,Nigel Trudgill,Praful Patel,Philip Kaye,Scott Sanders,M O'Donovan,Elizabeth L. Bird-Lieberman,Pradeep Bhandari,Janusz Jankowski,Stephen Attwood,Simon L. Parsons,Duncan Loft,Jesper Lagergren,Paul Moayyedi,Georgios Lyratzopoulos,John de Caestecker +20 more
TL;DR: These guidelines provide a practical and evidence-based resource for the management of patients with Barrett's oesophagus and related early neoplasia and suggested stratification of patients according to their estimated cancer risk based on clinical and histopathological criteria for the first time.
Journal ArticleDOI
Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial
K. Nadine Phoa,Frederike G. Van Vilsteren,Bas L. Weusten,Raf Bisschops,Erik J. Schoon,Krish Ragunath,Grant Fullarton,Massimiliano di Pietro,Narayanasamy Ravi,Mike Visser,G. Johan A. Offerhaus,Cees A. Seldenrijk,Sybren L. Meijer,Fiebo J.W. ten Kate,Jan G.P. Tijssen,Jacques J. Bergman +15 more
TL;DR: Radiofrequency ablation resulted in a reduced risk of neoplastic progression over 3 years of follow-up and the data and safety monitoring board recommended early termination of the trial due to superiority of ablation for the primary outcome and the potential for patient safety issues if the trial continued.
Journal ArticleDOI
Consensus Statements for Management of Barrett's Dysplasia and Early-Stage Esophageal Adenocarcinoma, Based on a Delphi Process
Cathy Bennett,Nimish Vakil,Jacques J. Bergman,Rebecca Harrison,Robert D. Odze,Michael Vieth,Scott Sanders,Oliver Pech,Gaius Longcroft-Wheaton,Yvonne Romero,John M. Inadomi,Jan Tack,Douglas A. Corley,Hendrik Manner,Susi Green,David Al Dulaimi,Haythem Ali,Bill Allum,Mark R Anderson,Howard Curtis,Gary W. Falk,M. Brian Fennerty,Grant Fullarton,Kausilia K. Krishnadath,Stephen J. Meltzer,David Armstrong,Robert A. Ganz,Gianpaolo Cengia,James J. Going,John R. Goldblum,Charles Gordon,Heike I. Grabsch,Chris Haigh,Michio Hongo,David Johnston,Ricky Forbes-Young,Elaine Kay,Philip Kaye,Toni Lerut,Laurence Lovat,Lars Lundell,Philip Mairs,Tadakuza Shimoda,Stuart J. Spechler,Stephen J. Sontag,Peter Malfertheiner,Iain A. Murray,Manoj Nanji,David N. Poller,Krish Ragunath,Jaroslaw Regula,Renzo Cestari,Neil A. Shepherd,Rajvinder Singh,Hubert J. Stein,Nicholas J. Talley,Jean Paul Galmiche,Tony C.K. Tham,Peter Watson,Lisa Yerian,Massimo Rugge,Thomas W. Rice,John Hart,Stuart Gittens,David Hewin,Juergen Hochberger,Peter J. Kahrilas,Sean L. Preston,Richard E. Sampliner,Prateek Sharma,Robert C. Stuart,Kenneth K. Wang,Irving Waxman,Chris Abley,Duncan Loft,Ian D. Penman,Nicholas J. Shaheen,Amitabh Chak,Gareth Davies,L. J. Dunn,Yngve Falck-Ytter,John deCaestecker,Pradeep Bhandari,Christian Ell,S. Michael Griffin,Stephen Attwood,Hugh Barr,John J.B. Allen,Mark K. Ferguson,Paul Moayyedi,Janusz Jankowski,Janusz Jankowski,Janusz Jankowski +92 more
TL;DR: An international, multidisciplinary, systematic, evidence-based review of different management strategies for patients with Barrett's esophagus and dysplasia or early-stage EA and developed a data-sifting platform and used the Delphi process to create evidence- based consensus statements.
Journal ArticleDOI
The role of endoscopy in Barrett's esophagus and other premalignant conditions of the esophagus.
John A. Evans,Dayna S. Early,Norio Fukami,Tamir Ben-Menachem,Vinay Chandrasekhara,Krishnavel V. Chathadi,G. Anton Decker,Robert D. Fanelli,Deborah A. Fisher,Kimberly Foley,Joo Ha Hwang,Rajeev Jain,Terry L. Jue,Khalid Khan,Jenifer R. Lightdale,Phyllis M. Malpas,John T. Maple,Shabana F. Pasha,John R. Saltzman,Ravi Sharaf,Amandeep K. Shergill,Jason A. Dominitz,Brooks D. Cash +22 more
TL;DR: In this paper, the Standards of Practice Committee of the American Society for Gastrointestinal Endoscopy prepared a series of statements discussing the use of GI endoscopy in common clinical situations.
Journal ArticleDOI
Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel
Lucas C. Duits,K. Nadine Phoa,Wouter L. Curvers,Fiebo J.W. ten Kate,Gerrit A. Meijer,Cees A. Seldenrijk,G. Johan A. Offerhaus,Mike Visser,Sybren L. Meijer,Kausilia K. Krishnadath,Jan G.P. Tijssen,R.C. Mallant-Hent,Jacques J. Bergman +12 more
TL;DR: Confirmed LGD in BO has a markedly increased risk of malignant progression, however, the vast majority of patients with community LGD will be downstaged after expert review and have a low progression risk.
References
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Journal ArticleDOI
The diagnosis of low-grade dysplasia in Barrett's esophagus and its implications for disease progression.
Marek Skacel,Robert E. Petras,Terry Gramlich,Jessica E. Sigel,Joel E. Richter,John R. Goldblum +5 more
TL;DR: A consensus diagnosis of LGD among GI pathologists suggests an increased risk of progression from LGD to HGD or carcinoma, and a high degree of interobserver variability is seen in the histological diagnosis of Barrett's esophagus–related LGD.
Journal ArticleDOI
The incidence of adenocarcinoma and dysplasia in Barrett's esophagus: Report on the cleveland clinic barrett's esophagus registry
TL;DR: The incidence of adenocarcinoma and dysplasia in Barrett's esophagus was reported in the cleveland clinic barrett's Esophagus registry.
Journal ArticleDOI
Dysplasia as a predictive marker for invasive carcinoma in Barrett esophagus: a follow-up study based on 138 cases from a diagnostic variability study.
Elizabeth A. Montgomery,John R. Goldblum,Joel K. Greenson,Marian M. Haber,Laura W. Lamps,Gregory Y. Lauwers,Audrey J. Lazenby,David N. Lewin,Marie E. Robert,K. A. Y. Washington,Marianna Zahurak,John Hart +11 more
TL;DR: The data obtained from submitted diagnoses as opposed to those from blind review suggest that knowledge of the clinical findings aids in diagnosis, and support the assertion that HGD is strongly associated with invasive carcinoma.
Journal ArticleDOI
Risk of malignant progression in patients with Barrett's oesophagus: a Dutch nationwide cohort study
Pieter J F de Jonge,Mark van Blankenstein,Caspar W. N. Looman,M.K. Casparie,Gerrit A. Meijer,Ernst J. Kuipers +5 more
TL;DR: Male sex, older age and LGD at diagnosis are independent predictors of malignant progression, and should enable an improved risk assessment in Barrett's oesophagus, in this largest reported cohort of unselected patients with BO.
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