Sex and gender: modifiers of health, disease, and medicine.
Franck Mauvais-Jarvis,Noel Bairey Merz,Peter J. Barnes,Roberta Diaz Brinton,Juan Jesus Carrero,Dawn L. DeMeo,Geert J. De Vries,C. Neill Epperson,Ramaswamy Govindan,Sabra L. Klein,Amedeo Lonardo,Pauline M. Maki,Louise D. McCullough,Vera Regitz-Zagrosek,Vera Regitz-Zagrosek,Judith G. Regensteiner,Joshua B. Rubin,Kathryn Sandberg,Ayako Suzuki,Ayako Suzuki +19 more
TLDR
Clinicians and researchers are guided to consider sex and gender in their approach to diagnosis, prevention, and treatment of diseases as a necessary and fundamental step towards precision medicine, which will benefit men's and women's health.About:
This article is published in The Lancet.The article was published on 2020-08-22 and is currently open access. It has received 781 citations till now. The article focuses on the topics: Sex characteristics & Disease.read more
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Sex differences in longitudinal trajectories of cognitive aging in Zaragoza, Spain
Elena Lobo,Antonio Lobo,Patricia Gracia-García,Raúl López-Antón,Pedro Saz,Concepción de la Cámara +5 more
TL;DR: In this paper , the longitudinal trajectories of cognitive aging in a sample of cognitively healthy subjects of 55 years or older were documented, and differences between men and women were hypothesized: 1) in the cognitive loss through aging, 2) in distinct trajectories identified; and 3) in predictors associated with the identified trajectories.
Journal ArticleDOI
A machine-learning based bio-psycho-social model for the prediction of non-obstructive and obstructive coronary artery disease.
Valeria Raparelli,GiulioF Romiti,Giulia Di Teodoro,R. Seccia,Gaetano Tanzilli,Nicola Viceconte,Ramona Marrapodi,Davide Flego,Bernadette Corica,Roberto Cangemi,Louise Pilote,Stefania Basili,Marco Proietti,Laura Palagi,Lucia Stefanini +14 more
TL;DR: In this article , the authors developed a machine-learning model for the supervised prediction of obstructive versus non-obstructive coronary artery disease (CAD), and the interplay between clinical, functional, biological and psycho-social features is still far to be fully elucidated.
Journal ArticleDOI
Sex Differences in GERD
TL;DR: This article found that premenopausal females appear to be protected from esophageal mucosal damage, as they demonstrate lower rates of erosive reflux disease, Barrett's esophagus, and adenocarcinoma.
Journal ArticleDOI
Fundamental neurochemistry review: Old brain stories ‐ Influence of age and sex on the neurodegeneration‐associated lipid changes
Lorena Cuenca-Bermejo,Alessandro Prinetti,Karolina Kublickiene,Valeria Raparelli,Alexandra Kautzky-Willer,Colleen M. Norris,Louise Pilote,Maria Trinidad Herrero +7 more
TL;DR: In this article, the presence of sex differences in the brain lipid changes that occur along aging, and in the two most common age-related neurodegenerative disorders (Alzheimer's and Parkinson's diseases).
Journal ArticleDOI
Editorial: Women's Lung
References
More filters
Journal ArticleDOI
Hallmarks of cancer: the next generation.
TL;DR: Recognition of the widespread applicability of these concepts will increasingly affect the development of new means to treat human cancer.
Journal ArticleDOI
Clinical Characteristics of Coronavirus Disease 2019 in China.
Wei-jie Guan,Zhengyi Ni,Yu Hu,Wenhua Liang,Chun-Quan Ou,Jianxing He,Lei Liu,Hong Shan,Chunliang Lei,David S.C. Hui,Bin Du,Lanjuan Li,Guang Zeng,Kowk-Yung Yuen,Ruchong Chen,Chun-Li Tang,Tao Wang,Ping-Yan Chen,Jie Xiang,Shiyue Li,Jinlin Wang,Zi-jing Liang,Yi-xiang Peng,Li Wei,Yong Liu,Ya-hua Hu,Peng Peng,Jian-ming Wang,Ji-yang Liu,Zhong Chen,Gang Li,Zhi-jian Zheng,Shao-qin Qiu,Jie Luo,Chang-jiang Ye,Shao-yong Zhu,Nanshan Zhong +36 more
TL;DR: During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness, and patients often presented without fever, and many did not have abnormal radiologic findings.
Journal ArticleDOI
Cancer statistics, 2017
TL;DR: The American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival.
Journal ArticleDOI
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Salim Yusuf,Steven Hawken,Stephanie Ôunpuu,Tony Dans,Alvaro Avezum,Fernando Lanas,Matthew J. McQueen,Andrzej Budaj,Prem Pais,John Varigos,Liu Lisheng +10 more
TL;DR: Abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity account for most of the risk of myocardial infarction worldwide in both sexes and at all ages in all regions.
Journal ArticleDOI
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area.
Safiya Richardson,Safiya Richardson,Jamie S. Hirsch,Jamie S. Hirsch,Mangala Narasimhan,James M. Crawford,Thomas McGinn,Thomas McGinn,Karina W. Davidson,Karina W. Davidson,Douglas P. Barnaby,Douglas P. Barnaby,Lance B Becker,John Chelico,John Chelico,Stuart L. Cohen,Stuart L. Cohen,Jennifer Cookingham,Kevin Coppa,Michael A Diefenbach,Andrew J. Dominello,Joan Duer-Hefele,Louise Falzon,Jordan Gitlin,Negin Hajizadeh,Negin Hajizadeh,Tiffany G. Harvin,David Hirschwerk,Eun Ji Kim,Eun Ji Kim,Zachary Kozel,Lyndonna Marrast,Lyndonna Marrast,Jazmin N. Mogavero,Gabrielle A. Osorio,Michael Qiu,Theodoros P. Zanos +36 more
TL;DR: This case series provides characteristics and early outcomes of sequentially hospitalized patients with confirmed COVID-19 in the New York City area and assesses outcomes during hospitalization, such as invasive mechanical ventilation, kidney replacement therapy, and death.
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