Sperm navigation along helical paths in 3D chemoattractant landscapes.
Jan F. Jikeli,Luis Alvarez,Benjamin M. Friedrich,Laurence G. Wilson,René Pascal,Remy Colin,Magdalena Pichlo,Andreas Rennhack,Christoph Brenker,U. Benjamin Kaupp +9 more
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TLDR
This work tracks sea urchin sperm navigating in 3D chemoattractant gradients using holographic microscopy and optochemical techniques and provides a conceptual and technical framework for studying microswimmers in3D chemical landscapes.Citations
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Sperm-Hybrid Micromotor for Targeted Drug Delivery
Haifeng Xu,Mariana Medina-Sánchez,Veronika Magdanz,Lukas Schwarz,Franziska Hebenstreit,Oliver G. Schmidt +5 more
TL;DR: In this paper, a sperm-driven micromotor is presented as a targeted drug delivery system, which is appealing to potentially treat diseases in the female reproductive tract, and is demonstrated to be an efficient drug delivery vehicle by first loading a motile sperm cell with an anticancer drug (doxorubicin hydrochloride), guiding it magnetically, to an in vitro cultured tumor spheroid, and finally freeing the sperm cell to deliver the drug locally.
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The 2020 motile active matter roadmap
Gerhard Gompper,Roland G. Winkler,Thomas Speck,Alexandre Solon,Cesare Nardini,Fernando Peruani,Hartmut Löwen,Ramin Golestanian,Ramin Golestanian,U. Benjamin Kaupp,Luis Alvarez,Thomas Kiørboe,Eric Lauga,Wilson C. K. Poon,Antonio DeSimone,Santiago Muiños-Landin,Alexander Fischer,Nicola Andreas Söker,Frank Cichos,Raymond Kapral,Pierre Gaspard,Marisol Ripoll,Francesc Sagués,Amin Doostmohammadi,Julia M. Yeomans,Igor S. Aranson,Clemens Bechinger,Holger Stark,Charlotte K. Hemelrijk,François Nédélec,Trinish Sarkar,Thibault Aryaksama,Mathilde Lacroix,Guillaume Duclos,Victor Yashunsky,Pascal Silberzan,Marino Arroyo,Sohan Kale +37 more
TL;DR: The 2019 motile active matter roadmap of Journal of Physics: Condensed Matter addresses the current state of the art of the field and provides guidance for both students as well as established scientists in their efforts to advance this fascinating area as discussed by the authors.
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Phototaxis of synthetic microswimmers in optical landscapes
TL;DR: It is experimentally demonstrated that sensing of light gradients can also be achieved in a system of synthetic photo-activated microparticles being exposed to an inhomogeneous laser field, and a strong orientational response of the particles because of diffusiophoretic torques is observed.
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Microfluidics for sperm analysis and selection
Reza Nosrati,Percival J. Graham,Biao Zhang,Jason Riordon,Alexander Lagunov,Thomas Hannam,Carlos Escobedo,Keith Jarvi,David Sinton +8 more
TL;DR: Many burgeoning possibilities exist for engineers, biologists, and clinicians to improve current practices for infertility diagnosis and treatment, and the most promising avenues have the potential to improve medical practice.
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Acoustic actuation of bioinspired microswimmers
Murat Kaynak,Adem Ozcelik,Amir Nourhani,Paul E. Lammert,Vincent H. Crespi,Tony Jun Huang,Tony Jun Huang +6 more
TL;DR: Acoustic actuation of bioinspired microswimmers is experimentally demonstrated and simple microfabrication and remote actuation are promising for biomedical applications.
References
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Fundamentals of Photonics
TL;DR: The Fundamentals of Photonics, Third Edition as discussed by the authors is a self-contained and up-to-date introductory-level textbook that thoroughly surveys this rapidly expanding area of engineering and applied physics.
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A New Sensitive Chemical Actinometer. II. Potassium Ferrioxalate as a Standard Chemical Actinometer
C. G. Hatchard,C. A. Parker +1 more
TL;DR: In this paper, a detailed study has been made of the photolysis of the acidified solutions previously recommended for chemical actinometry, and accurate values of quantum efficiency have been determined at twelve wavelengths between 254 and 578 m$\mu $, and the effect of temperature, light intensity and of photolyte composition have been investigated.
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Chemotaxis in Escherichia coli analysed by Three-dimensional Tracking
Howard C. Berg,Douglas A. Brown +1 more
TL;DR: Chemotaxis toward amino-acids results from the suppression of directional changes which occur spontaneously in isotropic solutions.
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Robustness in simple biochemical networks
Naama Barkai,Stanislas Leibler +1 more
TL;DR: It is argued that the key properties of biochemical networks should be robust in order to ensure their proper functioning, and it is shown that this applies in particular to bacterial chemotaxis.