Journal ArticleDOI
Striatal Shati/Nat8l-BDNF pathways determine the sensitivity to social defeat stress in mice through epigenetic regulation.
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In this article, the role of Shati/Nat8l in stress sensitivity in mice was investigated and it was found that Shati and N8l levels in the dorsal striatum were increased in stress-susceptible mice but not in resilient mice exposed to repeated social defeat stress (RSDS).About:
This article is published in Neuropsychopharmacology.The article was published on 2021-06-07. It has received 13 citations till now. The article focuses on the topics: Tropomyosin receptor kinase B & Chronic stress.read more
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Shati/Nat8l Overexpression Improves Cognitive Decline by Upregulating Neuronal Trophic Factor in Alzheimer’s Disease Model Mice
Kakeru Chino,Naotaka Izuo,H Noike,Kyosuke Uno,Tomoharu Kuboyama,Chihiro Tohda,Shin-ichi Muramatsu,Atsumi Nitta +7 more
TL;DR: Results suggest that Shati/Nat8l overexpression prevents cognitive dysfunction in 5XFAD mice, indicating that Shatisati/ Nat8l could be a therapeutic target for AD.
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Knockdown of Piccolo in the Nucleus Accumbens Suppresses Methamphetamine-Induced Hyperlocomotion and Conditioned Place Preference in Mice
References
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G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences
TL;DR: G*Power 3 provides improved effect size calculators and graphic options, supports both distribution-based and design-based input modes, and offers all types of power analyses in which users might be interested.
Journal ArticleDOI
Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses.
TL;DR: In the new version, procedures to analyze the power of tests based on single-sample tetrachoric correlations, comparisons of dependent correlations, bivariate linear regression, multiple linear regression based on the random predictor model, logistic regression, and Poisson regression are added.
Book
The Mouse Brain in Stereotaxic Coordinates
TL;DR: The 3rd edition of this atlas is now in more practical 14"x11" format for convenient lab use and includes a CD of all plates and diagrams, as well as Adobe Illustrator files of the diagrams, and a variety of additional useful material.
Journal ArticleDOI
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression
Carlos A. Zarate,Jaskaran Singh,Paul J. Carlson,Nancy E. Brutsche,Rezvan Ameli,David A. Luckenbaugh,Dennis S. Charney,Husseini K. Manji +7 more
TL;DR: Robust and rapid antidepressant effects resulted from a single intravenous dose of an N-methyl-D-aspartate antagonist; onset occurred within 2 hours postinfusion and continued to remain significant for 1 week.
Journal ArticleDOI
The molecular neurobiology of depression
TL;DR: Recent studies combining behavioural, molecular and electrophysiological techniques reveal that certain aspects of depression result from maladaptive stress-induced neuroplastic changes in specific neural circuits and show that understanding the mechanisms of resilience to stress offers a crucial new dimension for the development of fundamentally novel antidepressant treatments.