Journal ArticleDOI
Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve.
TLDR
Pure populations of Schwann cells are derived from dissociated cultures of neonatal rat sciatic nerve that express the S100 antigen, as shown by indirect immunofluorescence and complement fixation, and receptors for cholera toxin.About:
This article is published in Brain Research.The article was published on 1979-04-06. It has received 1071 citations till now. The article focuses on the topics: Schwann cell proliferation & Schwann cell differentiation.read more
Citations
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Journal ArticleDOI
GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle
Christopher E. Henderson,Heidi S. Phillips,Richard A. Pollock,Alun M. Davies,Corinne Lemeulle,Mark Armanini,Lora C. Simpson,Barbara Moffet,Richard Vandlen,Vassilis E. Koliatsos,Arnon Rosenthal +10 more
TL;DR: Glial cell line-derived neurotrophic factor (GDNF), originally identified as a trophic factor specific for dopaminergic neurons, was found to be 75-fold more potent than the neurotrophins in supporting the survival of purified embryonic rat motoneurons in culture and to be a good candidate for treatment of motoneuron disease.
Journal ArticleDOI
Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture
Martin Raff,Martin Raff,Kay L. Fields,Kay L. Fields,Sen-itiroh Hakomori,Sen-itiroh Hakomori,Rhona Mirsky,Rhona Mirsky,Rebecca M. Pruss,Rebecca M. Pruss,Janet Winter,Janet Winter +11 more
TL;DR: Although Ran-1 is expressed on glial and neuronal tumours, it was not found on normal astrocytes, oligodendrocyte or neurons and the 'large external transformation sensitive' (LETS) protein could be detected on fibroblasts and leptomeningeal cells but not on neurons or glial cells.
Journal ArticleDOI
Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system.
Mark A. Marchionni,Andrew Goodearl,Maio Su Chen,Olivia Bermingham-McDonogh,Cassandra Kirk,Marvin Hendricks,Frank Danehy,Don Misumi,Judith Sudhalter,Kazumi Kobayashi,Diana Wroblewski,Catherine Lynch,Mark Baldassare,Ian Hiles,John B. Davis,John B. Davis,J. Justin Hsuan,Nicholas F. Totty,Masayuki Otsu,Robert N. McBurney,Michael D. Waterfield,Paul Stroobant,David I. Gwynne +22 more
TL;DR: Alternative splicing of the messenger RNA generates an array of putative membrane-attached, intracellular and secreted signalling proteins, at least some of which are expressed in the developing spinal cord and brain.
Journal ArticleDOI
Krox-20 controls myelination in the peripheral nervous system.
Piotr Topilko,Sylvie Schneider-Maunoury,Giovanni Levi,A. Baron-Van Evercooren,Amina Ben Younes Chennoufi,Tania Seitanidou,Charles Babinet,Patrick Charnay +7 more
TL;DR: It is demonstrated here that Krox-20 is also activated in Schwann cells before the onset of myelination and that its disruption blocks Schwann Cells at an early stage in their differentiation, thus preventing myelinations in the peripheral nervous system.
Journal ArticleDOI
Sox10, a Novel Transcriptional Modulator in Glial Cells
TL;DR: A role for Sox10 is proposed in conferring cell specificity to the function of other transcription factors in developing and mature glia, including Pax3 and Krox-20, twoother transcription factors involved in Schwann cell development.
References
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Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells.
James G. Rheinwatd,Howard Green +1 more
TL;DR: Human diploid epidermis epidermal cells have been successfully grown in serial culture and it is possible to isolate keratinocyte clones free of viable fibroblasts, and human diploids keratinocytes appear to have a finite culture lifetime.
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Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma
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TL;DR: From a transplantable mouse teratoma it has been possible to derive an established keratinizing cell line (XB) which grows well in cultures containing lethally irradiated 3T3 fibroblasts at the correct density.
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The akr thymic antigen and its distribution in leukemias and nervous tissues
Arnold E. Reif,Joan M. Allen +1 more
TL;DR: A clear-cut serological differentiation between AKR lymphocytes of thymic and non-thymic origin is reported: these two cell types are antigenically distinct.
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Purification of a fibroblast growth factor from bovine pituitary.
TL;DR: The purification from bovine pituitary gland of a growth factor responsible for the control of animal cell division in tissue culture is reported.
Journal ArticleDOI
Astrocyte-specific protein and neuroglial differentiation. An immunofluorescence study with antibodies to the glial fibrillary acidic protein.
Amico Bignami,Doris Dahl +1 more
TL;DR: In the mature brain and spinal cord the distribution and appearance of neuroglia as observed with immunofluorescence were similar to those described by Weigert ('95) using his method for astrocytic fibers.
Related Papers (5)
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