Superoxide Dismutase AN ENZYMIC FUNCTION FOR ERYTHROCUPREIN (HEMOCUPREIN)
Joe M. McCord,Irwin Fridovich +1 more
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The demonstration that O2·- can reduce ferricytochrome c and tetranitromethane, and that superoxide dismutase, by competing for the superoxide radicals, can markedly inhibit these reactions, is demonstrated.About:
This article is published in Journal of Biological Chemistry.The article was published on 1969-11-25 and is currently open access. It has received 12468 citations till now. The article focuses on the topics: Copper chaperone for superoxide dismutase & Superoxide reductase.read more
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The inhibition of low-density lipoprotein oxidation by 17-β estradiol
TL;DR: The results indicate that estrogen may protect against atherosclerosis by inhibiting lipoprotein oxidation.
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The oxidative stress caused by salinity in two barley cultivars is mitigated by elevated CO2.
Usue Pérez-López,Anabel Robredo,Maite Lacuesta,Cristina Sgherri,Alberto Muñoz-Rueda,Flavia Navari-Izzo,Amaia Mena-Petite +6 more
TL;DR: It can be concluded that elevated CO(2) mitigates the oxidative stress caused by salinity, involving lower ROS generation and a better maintenance of redox homeostasis as a consequence of higher assimilation rates and lower photorespiration, being the response dependent on the cultivar analysed.
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Physiological changes of sturgeon Acipenser naccarii caused by increasing environmental salinity.
Rosa M. Martínez-Álvarez,M.C. Hidalgo,A. Domezain,Amalia E. Morales,M. García-Gallego,Albina Sanz +5 more
TL;DR: C cortisol values, antioxidant enzyme activities in the blood, lipid peroxidation in plasma, and hepatic proteins did not return to initial values, showing that osmoregulatory processes cause major physiological changes in the fish.
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Contaminant-induced oxidative stress in fish: a mechanistic approach
TL;DR: This review describes general aspects of ROS homeostasis, in particular highlighting its basic aspects, modification of cellular constituents, operation of defense systems and ROS-based signaling with an emphasis on fish systems.
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Superoxide Production and Antioxidant Enzymes in Ammonia Intoxication in Rats
TL;DR: Both diminished activity of antioxidant enzymes and increased superoxide radical production could lead to oxidative stress and cell damage, which could be involved in the mechanism of acute ammonia toxicity.
References
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The Reduction of Cytochrome c by Milk Xanthine Oxidase
Joe M. McCord,Irwin Fridovich +1 more
TL;DR: The data are consistent with the conclusion that xanthine oxidase generates an unstable reduced form of oxygen, presumably the superoxide anion, and that this radical is the agent which directly reduces cytochrome c and initiates the sulfite-oxygen chain reaction.
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The microestimation of succinate and the extinction coefficient of cytochrome c.
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The Preparation and Properties of Deflavo Xanthine Oxidase
TL;DR: The deflavoenzyme is catalytically active in the oxidation of xanthine with acceptors such as ferricyanide and cytochrome c.
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The mechanism of aerobic oxidase reaction catalyzed by peroxidase.
TL;DR: It has been found that peroxidase catalyzes the formation of free radicals of hydrogen donors in the presence of H 2 O 2, and Compound III is not an active intermediate for dihydroxyfumarate oxidation.
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Electron-spin-resonance evidence for enzymic reduction of oxygen to a free radical, the superoxide ion.
TL;DR: It is concluded that the species observed is the superoxide ion, O(2) (-), and that the stability of this ion is greatly increased in alkaline solution.