Superoxide Dismutase AN ENZYMIC FUNCTION FOR ERYTHROCUPREIN (HEMOCUPREIN)
Joe M. McCord,Irwin Fridovich +1 more
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The demonstration that O2·- can reduce ferricytochrome c and tetranitromethane, and that superoxide dismutase, by competing for the superoxide radicals, can markedly inhibit these reactions, is demonstrated.About:
This article is published in Journal of Biological Chemistry.The article was published on 1969-11-25 and is currently open access. It has received 12468 citations till now. The article focuses on the topics: Copper chaperone for superoxide dismutase & Superoxide reductase.read more
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Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury.
Jonathan R. Wispé,Barbara B. Warner,Jean C. Clark,Chitta R. Dey,J. Neuman,Stephan W. Glasser,J. D. Crapo,Ling-Yi Chang,Jeffrey A. Whitsett +8 more
TL;DR: The finding that increased Mn-SOD in distal respiratory epithelial cells confers protection from oxygen injury provides a basis for novel therapies to protect lung from injury during oxygen therapy of acute and chronic lung diseases.
Journal ArticleDOI
Manganese import is a key element of the OxyR response to hydrogen peroxide in Escherichia coli
TL;DR: It is found that manganese does not protect peroxide‐stressed cells by scavenging peroxide, and the beneficial effects ofManganese correlate with its ability to metallate mononuclear enzymes, which may prevent protein damage.
Journal ArticleDOI
Microplastics effects in Scrobicularia plana.
Francisca Ribeiro,Ana R. Garcia,Beatriz P. Pereira,Maria José Vieira Fonseca,Nélia C. Mestre,Taina Garcia da Fonseca,Laura M. Ilharco,Maria João Bebianno +7 more
TL;DR: Results revealed that microplastics induce effects on antioxidant capacity, DNA damage, neurotoxicity and oxidative damage, and that S. plana is a significant target to assess the environmental risk of PS microplastic.
Journal ArticleDOI
Superoxide anion permeability of phospholipid membranes and chloroplast thylakoids
Masaaki Takahashi,Kozi Asada +1 more
TL;DR: The permeability of phospholipid membranes to the superoxide anion (O-2) was determined using soybean phospholIPid vesicles containing FMN in the internal space and chloroplast thylakoids showed little permeability to O-2.
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Reversible conversion of nitroxyl anion to nitric oxide by superoxide dismutase.
Michael E. P. Murphy,Helmut Sies +1 more
TL;DR: It is reported that SOD supports a reversible reduction of NO to NO - and that NO- may be a physiologically important form of endothelium-derived relaxing factor.
References
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The Reduction of Cytochrome c by Milk Xanthine Oxidase
Joe M. McCord,Irwin Fridovich +1 more
TL;DR: The data are consistent with the conclusion that xanthine oxidase generates an unstable reduced form of oxygen, presumably the superoxide anion, and that this radical is the agent which directly reduces cytochrome c and initiates the sulfite-oxygen chain reaction.
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The microestimation of succinate and the extinction coefficient of cytochrome c.
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The Preparation and Properties of Deflavo Xanthine Oxidase
TL;DR: The deflavoenzyme is catalytically active in the oxidation of xanthine with acceptors such as ferricyanide and cytochrome c.
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The mechanism of aerobic oxidase reaction catalyzed by peroxidase.
TL;DR: It has been found that peroxidase catalyzes the formation of free radicals of hydrogen donors in the presence of H 2 O 2, and Compound III is not an active intermediate for dihydroxyfumarate oxidation.
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Electron-spin-resonance evidence for enzymic reduction of oxygen to a free radical, the superoxide ion.
TL;DR: It is concluded that the species observed is the superoxide ion, O(2) (-), and that the stability of this ion is greatly increased in alkaline solution.