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Journal ArticleDOI

Surface engineering approaches to micropattern surfaces for cell-based assays.

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TLDR
The focus of this review is on the surface engineering aspects of biologically motivated micropatterning of two-dimensional (flat) surfaces with the aim to provide an introductory overview and critical assessment of the many techniques described in the literature.
About
This article is published in Biomaterials.The article was published on 2006-06-01. It has received 943 citations till now. The article focuses on the topics: Micropatterning.

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Citations
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Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink

TL;DR: The versatility and flexibility of the developed bioprinting process using tissue-specific dECM bioinks, including adipose, cartilage and heart tissues, capable of providing crucial cues for cells engraftment, survival and long-term function are shown.
Journal ArticleDOI

3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications

TL;DR: A bioink that combines the outstanding shear thinning properties of nanofibrillated cellulose (NFC) with the fast cross-linking ability of alginate with the potential use of nanocellulose for 3D bioprinting of living tissues and organs is formulated.
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Printing and Prototyping of Tissues and Scaffolds

TL;DR: New manufacturing technologies under the banner of rapid prototyping enable the fabrication of structures close in architecture to biological tissue, and such techniques have opened new areas of research in tissue engineering and regenerative medicine.
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Modulation of cell adhesion, proliferation and differentiation on materials designed for body implants.

TL;DR: The interaction of cells and tissues with artificial materials designed for applications in biotechnologies and in medicine is governed by the physical and chemical properties of the material surface, including surface roughness and surface topography.
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Polydopamine—a nature-inspired polymer coating for biomedical science

TL;DR: The basic chemistry and material science regarding PDA is outlined and its successful application from coatings for interfacing with cells, to drug delivery and biosensing is discussed.
References
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Journal ArticleDOI

Integrins: Bidirectional, Allosteric Signaling Machines

TL;DR: Current structural and cell biological data suggest models for how integrins transmit signals between their extracellular ligand binding adhesion sites and their cytoplasmic domains, which link to the cytoskeleton and to signal transduction pathways.
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Geometric control of cell life and death.

TL;DR: Human and bovine capillary endothelial cells were switched from growth to apoptosis by using micropatterned substrates that contained extracellular matrix-coated adhesive islands of decreasing size to progressively restrict cell extension.
Book

Biomaterials Science: An Introduction to Materials in Medicine

TL;DR: A. Ratner, Biomaterials Science: An Interdisciplinary Endeavor, Materials Science and Engineering--Properties of Materials: J.E. Schoen, and R.J.Ratner, Surface Properties of Materials, and Application of Materials in Medicine and Dentistry.
Journal ArticleDOI

Cell shape, cytoskeletal tension, and rhoa regulate stem cell lineage commitment

TL;DR: It is demonstrated that cell shape regulates commitment of human mesenchymal stem cells to adipocyte or osteoblast fate and mechanical cues experienced in developmental and adult contexts, embodied by cell shape, cytoskeletal tension, and RhoA signaling, are integral to the commitment of stem cell fate.
Journal ArticleDOI

Designing materials for biology and medicine

TL;DR: New challenges and directions in biomaterials research are discussed, including synthetic replacements for biological tissues, designing materials for specific medical applications, and materials for new applications such as diagnostics and array technologies.
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