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Open AccessJournal ArticleDOI

Synthesis of Carbon Quantum Dot Nanoparticles Derived from Byproducts in Bio-Refinery Process for Cell Imaging and In Vivo Bioimaging

TLDR
In this paper, the carbon quantum dot (CQD) was synthesized from byproducts derived from a biorefinery process using one-pot hydrothermal treatment.
Abstract
The carbon quantum dot (CQD), a fluorescent carbon nanoparticle, has attracted considerable interest due to its photoluminescent property and promising applications in cell imaging and bioimaging. In this work, biocompatible, photostable, and sustainably sourced CQDs were synthesized from byproducts derived from a biorefinery process using one-pot hydrothermal treatment. The main components of byproducts were the degradation products (autohydrolyzate) of biomass pretreated by autohydrolysis. The as-synthesized CQDs had a size distribution from 2.0–6.0 nm and had high percentage of sp2 and sp3 carbon groups. The CQDs showed blue-green fluorescence with a quantum yield of ~13%, and the fluorescence behaviors were found to be stable with strong resistance to photobleaching and temperature change. In addition, it is found that the as-synthesized CQDs could be used for imaging of cells and tumors, which show potential applications in bioimaging and related fields such as phototherapy and imaging.

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Citations
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Bacterial Cellulose-Based Composite Scaffolds for Biomedical Applications: A Review

TL;DR: Bacterial cellulose, with non-toxicity, high purity, and biocompatibility, has been considered as a versatile candidate for various biomedical applications and recently, the fabrication of BC-bas...
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Green synthesis, biomedical and biotechnological applications of carbon and graphene quantum dots. A review

TL;DR: Green methods for the fabrication of quantum dots, and biomedical and biotechnological applications are reviewed.
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Recent advances in carbon dots for bioimaging applications

TL;DR: This review article mainly outlines recent advances in the field of CD-based bioimaging and summarizes achievements in two broad categories: in vitro imaging in terms of the approaches to deliver CD- based probes into different types of cells and vital cell organelles, as well as in vivo applications that focus on distribution and uptake of CDs.
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A sustainable process for procuring biologically active fractions of high-purity xylooligosaccharides and water-soluble lignin from Moso bamboo prehydrolyzate.

TL;DR: The proposed strategy of sequentially combining hydrophobic resin separation, enzymatic hydrolysis, and fermentation was successfully demonstrated and resulted in simultaneous production of high-quality XOS and solubilized lignin, which can be regarded as value-adding prebiotics and antioxidants.
Journal ArticleDOI

A Review of Carbon Dots Produced from Biomass Wastes.

TL;DR: The fluorescent carbon dot is a novel type of carbon nanomaterial that possesses significant advantages such as excellent photostability and biocompatibility, low cytotoxicity and easy surface functionalization, which endow it a wide application prospect in fields of bioimaging, chemical sensing, environmental monitoring, disease diagnosis and photocatalysis.
References
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Journal ArticleDOI

Blue luminescent graphene quantum dots and graphene oxide prepared by tuning the carbonization degree of citric acid

TL;DR: An easy bottom-up method for the preparation of photoluminescent (PL) graphene quantum dots (GQDs) and graphene oxide (GO) has been developed by tuning the carbonization degree of citric acid and dispersing the carbonized products into alkaline solutions as mentioned in this paper.
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Deep ultraviolet photoluminescence of water-soluble self-passivated graphene quantum dots

TL;DR: The G QDs are capable of converting blue light into white light when the GQDs are coated onto a blue light emitting diode and the photoluminescence quantum yields were determined to be 7-11%.
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Highly luminescent carbon nanodots by microwave-assisted pyrolysis

TL;DR: Carbon nanodots with a low cytotoxicity have been synthesized by one-step microwave-assisted pyrolysis of citric acid in the presence of various amine molecules, confirmed to serve dual roles as N-doping precursors and surface passivation agents.
Journal ArticleDOI

Transforming C60 molecules into graphene quantum dots

TL;DR: It is shown that geometrically well-defined graphene quantum dots can be synthesized on a ruthenium surface using C(60) molecules as a precursor, and Scanning tunnelling microscopy imaging suggests that the structures are formed through the ruthene-catalysed cage-opening of C( 60).
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Electrochemical synthesis of small-sized red fluorescent graphene quantum dots as a bioimaging platform.

TL;DR: Water-soluble, 3 nm uniform-sized graphene quantum dots (GQDs) with red emission prepared by electrochemical exfoliation of graphite in K2S2O8 solution show a great potential as biological labels for cellular imaging.
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