Journal ArticleDOI
The genus Lindera: a source of structurally diverse molecules having pharmacological significance
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TLDR
Phytochemical investigations have shown that Lindera plants produce 341 constituents, including sesquiterpenoids, alkaloids, butanolides, lucidones, flavonoids, and phenylpropanoids, which have shown great potential in developing antiarthritic and antinociceptive agents.Abstract:
Lindera plants not only have good ornamental and economic uses but also have great medicinal and therapeutic values. The genus Lindera consists of approximately 100 species that are widely distributed in tropical and subtropical areas throughout the world. This extensive geographical distribution allows Lindera plants to produce diverse secondary metabolites having novel structures. Phytochemical investigations have shown that Lindera plants produce 341 constituents, including sesquiterpenoids, alkaloids, butanolides, lucidones, flavonoids, and phenylpropanoids. Moreover, some Lindera plants show significant chemotaxonomic reference under family Lauraceae and tribe Litseae. Although Lindera plants have various pharmacological and biological properties, their anticancer, antihypertensive, anti-inflammatory, and analgesic properties have been focused in many studies. Butanolides and lucidones have shown great potential in developing anticancer agents while aporphine alkaloids have shown great potential in developing antiarthritic and antinociceptive agents. However, these compounds need to be assessed further by performing in-depth and systematic research.read more
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Journal ArticleDOI
Comparative chloroplast genomics and phylogenetics of nine Lindera species (Lauraceae)
TL;DR: The results showed that these Lindera species grouped into two or four sub-clades, and that two Litsea species and Laurus nobilis were located in the same sub-Clade as five LinderA species, which support a close relationship between the genera Laurus, Lindersa, and Litsea.
Journal ArticleDOI
Atypical Lindenane-Type Sesquiterpenes from Lindera myrrha.
Thuc-Huy Duong,Mehdi A. Beniddir,Nguyen Tien Trung,Cam-Tu D. Phan,Van Giau Vo,Van-Kieu Nguyen,Quynh-Loan Le,Hoang-Dung Nguyen,Pierre Le Pogam +8 more
TL;DR: Two new lindenane sesquiterpenes were obtained from the roots of Lindera myrrha, and these compounds were structurally elucidated by HRMS data, extensive NMR analyses, and comparison between experimental and theoretical 13C-NMR data.
Journal ArticleDOI
Extraction and Isolation of Kaempferol Glycosides from the Leaves and Twigs of Lindera neesiana
TL;DR: The hydroalcoholic extract of leaves and twigs of Lindera neesiana (Wall. ex Nees) Kurz (Lauraceae) was subjected to various column chromatographic methods that isolated five kaempferol glycosides as mentioned in this paper.
Journal ArticleDOI
Flavonoids from the leaves and twigs of Lindera sericea (Seibold et Zucc.) Blume var. sericea (Lauraceae) from Japan and their bioactivities
Hari Prasad Devkota,Ayumi Kurizaki,Kazuki Tsushiro,Anjana Adhikari-Devkota,Kengo Hori,Mikiyo Wada,Takashi Watanabe +6 more
TL;DR: Kekuromoji et al. as discussed by the authors characterized the major phenolic compounds from the leaves and twigs of Lindera sericea and evaluated their free radical scavenging and α-glucosidase inhibitory activities.
Journal ArticleDOI
Lindera cyclopentenedione intermediates from the roots of Lindera aggregata
TL;DR: In this paper, NMR and MS data have been used to identify three new monomers of Lindera cyclopentenedione derivatives (1,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,
References
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Journal ArticleDOI
Changes in plant community diversity and floristic composition on environmental and geographical gradients
TL;DR: The predictability of the fioristic compositions and diversities of tropical forest plant communities eems strong, albeit circumstantial, evidence that these communities are at ecological and perhaps evolutionary equilibrium, despite indications that certain aspects of their diversity are generated and maintained stochastically.
Journal ArticleDOI
Synergy research: approaching a new generation of phytopharmaceuticals.
TL;DR: This review describes many examples of how modern molecular-biological methods can enable us to understand the various synergistic mechanisms underlying these effects of herbal drug combinations.
Journal ArticleDOI
Synergy research: approaching a new generation of phytopharmaceuticals.
TL;DR: Gallocatechins of green tea and curcuminoids of ginger are the presently favoured polyphenols for a possible future use in co-medication with antibiotics and standard anticancer drugs and the main targets were found to be COX 1+2, NF-κB, and membrane glycoproteins that belong to the ATP-binding cassette (ABC) transporter family.
Journal ArticleDOI
Revisiting the ancient concept of botanical therapeutics
TL;DR: Mixtures of interacting compounds produced by plants may provide important combination therapies that simultaneously affect multiple pharmacological targets and provide clinical efficacy beyond the reach of single compound-based drugs.
Journal ArticleDOI
Synthetic analgesics: stereochemical considerations.
A H Beckett,A F Casy +1 more
TL;DR: Active analgesics are shown to have structures which enable them to present similar surfaces to allow of their association with a proposed “analgesic receptor surface,” the essential features of which are described.